Aorta coarctation

This trial tests whether losartan, a common blood pressure medication, can reduce scarring in the heart's main pumping chamber and improve exercise capacity in adults who had surgery to repair coarctation of the aorta. Participants will take losartan, amlodipine, or a placebo dai…

This study tests whether a bedside device called Quantra can help doctors decide when to give blood transfusions during complex heart surgery. The device measures how well a patient's blood clots in real time. Researchers hope this will reduce the number of blood products (like r…

This study tests whether combining standard monitoring tools with new light-based sensors can better detect a dangerous narrowing of the aorta in newborns. Infants under one month old with suspected aortic arch obstruction will be monitored using resonance Raman spectroscopy, pul…

This study follows 50 adults who had surgery for coarctation of the aorta (a narrowed main artery). Researchers want to see if exercise-induced high blood pressure causes hidden damage to the heart, arteries, or kidneys. Participants will do a stress test, heart ultrasound, and b…

This study looks at how stenting a narrowed aorta (coarctation) changes the heart's workload. Researchers use a special catheter to measure pressure and volume inside the heart before and after stent placement. The goal is to understand if stenting fully improves heart function. …