Anodontia

This trial tests whether different 3D printing angles and layer thicknesses affect how accurately dentures fit and how satisfied patients are. Adults aged 50 to 70 with no teeth will each receive two 3D-printed upper dentures made with the same angle but different thicknesses, in…

This trial tests whether using digital jaw tracking to design full-arch implant-supported dentures leads to better fit and higher patient satisfaction compared to traditional methods. Twenty adults aged 50 to 70 with no upper teeth but with natural lower teeth will be randomly as…

This trial compares two types of full-arch dental implant frameworks—one made from a single piece of zirconia and the other from titanium with a zirconia top—in people who have lost all teeth in one or both jaws. The goal is to see which material leads to fewer mechanical problem…

This study tests three common cleaning aids—superfloss, interdental brushes, and a water flosser—in 18 adults with full-arch implant-supported dentures. Each person uses one method for three months, then switches to the next, so everyone tries all three. The goal is to find which…

This study tests a fully digital method for full-mouth dental rehabilitation in 10 adults aged 20-45 with bite problems, missing teeth, or smile concerns. The approach uses 3D scans of the teeth, face, and jaw to plan treatment, which may include tooth movement, guided implant pl…

This study tests whether a gel made from enamel proteins can thicken gum tissue around dental implants. Researchers will measure gum thickness in 32 adults who need implant uncovering surgery. The goal is to see if this treatment improves gum health and implant stability.

This study follows 100 people who are getting full-arch dental implants (replacing all teeth in one jaw). Researchers want to see how the treatment changes their oral health-related quality of life—things like eating, speaking, and feeling confident. Participants answer questionn…

This study compares two ways of making full dentures for people who have lost all their teeth. One method uses digital scans and 3D printing, while the other combines traditional impressions with digital design. Twenty participants will try both types of dentures for two months e…

This study compares two ways to secure lower dentures: using one implant or two implants. Researchers want to see if one implant can provide similar comfort, satisfaction, and chewing ability as two implants. The study involves 32 adults with no teeth who already have upper and l…

This study tests three different ways of taking digital impressions for lower jaw implant-supported dentures in people with no natural teeth. Each participant gets scanned with all three methods to see which one gives the most accurate implant positions and best fit. The goal is …

This trial tests whether a smartphone-based photogrammetry system (T-Marker) can match or beat a specialized intraoral scanner with splinting bodies (IoConnect) for recording implant positions in people with full-arch dental implants. Each participant will be scanned with both me…

This study looks at how the types of bacteria in the mouth change in people with severe gum disease as they go from having some teeth left to having no teeth, and then after getting dental implants. Researchers will collect microbial samples and analyze DNA to see if different im…

This study looks at how well dental implants heal in people taking TNF-alpha inhibitors (a type of arthritis medication). Researchers will compare 15 patients on these drugs with 15 similar patients not taking them. Participants will get implants and be followed for a year with e…

This study tests whether a digital intraoral scanner can capture the shape of the mouth as accurately as the traditional border-molded impression method for making complete dentures. Ten adults who have lost all their teeth will get both types of impressions, and researchers will…

This study looks at how quickly people can bite and slide their teeth when wearing a lower denture held in by either two regular-sized implants or four smaller mini-implants. Researchers will measure the time it takes to close the bite and to slide the teeth apart. The goal is to…

This study looks at how losing all your teeth and getting dentures affects your sense of taste, touch in the mouth, and food likes. Researchers will compare 40 people who have worn dentures for at least a year with 40 people who still have their natural teeth. The goal is to unde…