Acute tricyclic antidepressant poisoning
MONDO:0018547Acute tricyclic antidepressant (TCA) poisoning is a potentially lethal intoxication that is characterized by life-threatening arrhythmias (sinus tachycardias, premature ventricular contractions, ventricular arrhythmias), anticholinergic toxidrome (mydriasis, dry mucous membrane, tachycardia, hypertension), central nervous system toxicity (lethargy, coma, myoclonic jerks), refractory hypotension, and sudden death.
7 clinical trials for this condition and its sub-types.
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Can charcoal speed up poison recovery? new study aims to find out
Disease control Recruiting nowThis pilot study is testing whether giving activated charcoal within 6 hours of swallowing a poisonous substance can prevent the poison from getting worse and shorten hospital stays. About 100 adults and children who have ingested a substance that charcoal can absorb will be rand…
Phase: PHASE4 • Sponsor: Laval University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Computer alert aims to stop deadly clots after hospital stay
Prevention Recruiting nowThis study tests whether a computer alert can help doctors remember to prescribe blood-thinning medicine for high-risk patients after they leave the hospital. Blood clots are a serious risk for some hospitalized patients, even after discharge. The trial will include 400 adults ag…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Prevention
Last updated Jun 27, 2026 09:07 UTC
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Could a common Alzheimer's drug tame Poison-Induced delirium?
Symptom relief Recruiting nowThis study tests whether rivastigmine, a drug used for Alzheimer's, can quickly calm agitation and confusion caused by poisoning from medications that block certain nerve signals. About 42 people aged 10 and older with this type of delirium will receive either rivastigmine or a p…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC