Acute kidney tubular necrosis

This study tested a new ultrasound technique called URM to look at tiny blood vessels in the kidneys of 150 people with kidney failure. The goal was to see if this method can help doctors better assess kidney function, stage the disease, and monitor treatment. The researchers com…

This study tested a new wearable patch that collects sweat to measure sodium and creatinine levels, which are important for monitoring kidney health and dehydration. Five adults with kidney disease wore the patch while their sweat was analyzed using a special light-based techniqu…

This study tested whether giving fluids as a quick bolus or as a continuous drip works better to prevent kidney injury caused by contrast dye used in CT scans. The trial included 285 emergency department patients with high creatinine levels. Researchers measured kidney function 4…

This study looked at 287 patients with acute kidney injury caused by tubular necrosis. Researchers measured two substances in urine (PIIINP and NGAL) to see if they could predict whether kidney function would return or if chronic kidney disease would develop. The goal is to find …

This study looked at how a single dose of HR17031 moves through the body in people with mild, moderate, severe, or end-stage kidney disease compared to those with normal kidneys. A total of 24 adults with type 2 diabetes took part. The goal was to understand how kidney function a…

This completed Phase 1 study looked at how the drug LY3537982 is processed in people with different levels of kidney function. Researchers compared 32 participants with normal kidneys, moderate kidney problems, and severe kidney problems. The goal was to see how kidney impairment…

This study tracked 228 critically ill patients in China who needed continuous kidney dialysis. Doctors used pre-mixed solutions instead of custom-mixed ones to see how well they worked in everyday hospital care. The goal was to gather information on filter life, blood chemistry, …

This study looked at how different levels of kidney function affect the way the experimental brain drug iclepertin is processed in the body. 36 adults with and without kidney problems took a single dose of the drug. Researchers measured drug levels in the blood to see if kidney i…

This study looked at how the drug BI 1015550 is processed in people with and without kidney problems. 26 adults took a single dose, and researchers measured drug levels in their blood. The goal was to see if kidney impairment changes how the drug is absorbed, to guide future dosi…

This completed Phase 1 study looked at how the drug SHR8554 injection behaves in 20 people with kidney problems compared to healthy volunteers. The goal was to measure drug levels and safety, not to treat pain. Results will help guide future dosing for patients with kidney issues…

This study looked at whether the diabetes drug metformin can be used safely in people with type 2 diabetes who also have kidney disease. Researchers gave increasing doses of metformin to 82 patients with different stages of kidney failure and measured the drug levels in their red…

This completed Phase 1 study looked at how HRS-1893 tablets are processed in people with mild or moderate kidney impairment compared to healthy subjects. The goal was to understand dosing needs for patients with hypertrophic cardiomyopathy who also have kidney issues. Twenty-four…