Kidney function may change how this drug works

NCT ID NCT07137689

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 study looked at how the drug LY3537982 is processed in people with different levels of kidney function. Researchers compared 32 participants with normal kidneys, moderate kidney problems, and severe kidney problems. The goal was to see how kidney impairment affects drug levels in the blood, which helps determine the right dose for people with kidney issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LY3537982 (oral drug)

What this could lead to

If successful, this study could help doctors determine the right dose of LY3537982 for people with kidney problems, making the drug safer and more effective for them.

What could go wrong

This is a small, early-stage study focused on drug levels, not on treating a disease. It does not test whether LY3537982 works for any condition, so results may not lead to a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Genesis Clinical Research

    Tampa, Florida, 33603, United States

  • Jacksonville Center for Clinical Research

    Jacksonville, Florida, 32216, United States

  • Orlando Clinical Research Center

    Orlando, Florida, 32809, United States

  • Panax Clinical Research

    Miami Lakes, Florida, 33014, United States