Acidosis disorder

This trial tests whether taking oral sodium bicarbonate to correct metabolic acidosis can slow the buildup of calcium in the blood vessels of people on long-term hemodialysis. The study will include 40 adults who have been on dialysis for over six months and have low bicarbonate …

This study tested whether giving sodium bicarbonate (a common buffer) to critically ill patients with severe metabolic acidosis helps them survive and recover. 400 ICU patients with low blood pH and high lactate were randomly assigned to receive either sodium bicarbonate or no bu…

This study tested whether giving sodium bicarbonate (a common substance that neutralizes acid) to critically ill patients with severe metabolic acidosis and moderate-to-severe acute kidney injury could improve survival at 90 days. The trial enrolled 640 adults in the ICU who had …

This completed study tested whether eating more fruits and vegetables or taking sodium bicarbonate (baking soda) tablets can slow the progression of chronic kidney disease and reduce heart risks in people with high blood pressure and kidney damage. 108 non-diabetic adults with st…

This study tested two common drugs, ephedrine and norepinephrine, to treat low blood pressure during C-sections under spinal anesthesia. Low blood pressure can reduce blood flow to the baby, so doctors want the safest option. The trial included 102 pregnant women having planned C…

This completed study looked at 94 women who had a planned C-section under spinal anesthesia. Doctors compared two drugs used to prevent low blood pressure: a continuous drip of phenylephrine versus bolus injections of ephedrine. The main goal was to see which approach led to heal…