Which drug is safer for baby during C-Section? new study compares phenylephrine and ephedrine

NCT ID NCT06741410

Completed Knowledge-focused Sponsor: Centre of Postgraduate Medical Education Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed study looked at 94 women who had a planned C-section under spinal anesthesia. Doctors compared two drugs used to prevent low blood pressure: a continuous drip of phenylephrine versus bolus injections of ephedrine. The main goal was to see which approach led to healthier umbilical blood pH in newborns, a sign of how well the baby tolerated the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Phenylephrine and ephedrine
What this could lead to: If it works, this could help doctors choose the safer drug to maintain newborn health during cesarean delivery.
What could go wrong: This is a small, retrospective study, so results may not apply to all patients. It only looks at one measure of newborn well-being.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acidosis disorder hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CESAREAN DELIVERY NEONATAL ACIDOSIS SPINAL ANESTHESIA

Contacts and locations

Locations

Centre of Postgraduate Medical Education,Department of Anesthesia and Intensive Care

Warsaw, 01-813, Poland

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