Cure My Disease

Don't miss your cure!

 Log in / Sign up

C-Section drug showdown: which is safer for baby?

NCT ID NCT06921473

Disease control Sponsor: mehmet özkılıç Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two common drugs, ephedrine and norepinephrine, to treat low blood pressure during C-sections under spinal anesthesia. Low blood pressure can reduce blood flow to the baby, so doctors want the safest option. The trial included 102 pregnant women having planned C-sections. Researchers measured the baby's umbilical cord pH after birth to see which drug led to less acidosis (too much acid in the blood).

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ephedrine and norepinephrine
What this could lead to
If this trial shows one drug is safer for the baby, it could help doctors choose the best treatment for low blood pressure during C-sections.
What could go wrong
This is a small, completed Phase 4 trial with 102 participants. Results may not apply to all pregnancies, and both drugs have known side effects like rapid heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

102 people

The number who actually took part.

Started

Sep 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnant women aged between 18 and 45 years * Singleton pregnancy at ≥ 37 weeks of gestation * Scheduled for elective cesarean section under spinal anesthesia * ASA (American Society of Anesthesiologists) physical status classification I or II * Ability to understand and sign the informed consent form Exclusion Criteria: * History of allergy or hypersensitivity to ephedrine or norepinephrine * Multiple gestation pregnancies * Diagnosis of pre-eclampsia, eclampsia, or other hypertensive disorders of pregnancy * Known cardiovascular disease or arrhythmia * Placental abnormalities (e.g., placenta previa, placental abruption) * Fetal structural or chromosomal anomalies * Morbid obesity (BMI \> 40 kg/m²) * Refusal to participate or inability to provide informed consent

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Acidosis are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Acidosis acidosis disorder supine hypotensive syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acidosis Cesarean delivery affecting newborn Maternal hypotension Spinal aneshtesia

Contacts and locations

Locations

  • SBÜ Gazi Yaşargil Eğitim ve Araştırma Hastanesi

    Diyarbakır, 21070, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.