C-Section drug showdown: which is safer for baby?

NCT ID NCT06921473

Completed Disease control Sponsor: mehmet özkılıç Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two common drugs, ephedrine and norepinephrine, to treat low blood pressure during C-sections under spinal anesthesia. Low blood pressure can reduce blood flow to the baby, so doctors want the safest option. The trial included 102 pregnant women having planned C-sections. Researchers measured the baby's umbilical cord pH after birth to see which drug led to less acidosis (too much acid in the blood).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ephedrine and norepinephrine
What this could lead to: If this trial shows one drug is safer for the baby, it could help doctors choose the best treatment for low blood pressure during C-sections.
What could go wrong: This is a small, completed Phase 4 trial with 102 participants. Results may not apply to all pregnancies, and both drugs have known side effects like rapid heart rate.

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Conditions

The condition(s) this trial relates to.

Acidosis acidosis disorder supine hypotensive syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACIDOSIS CESAREAN DELIVERY AFFECTING NEWBORN MATERNAL HYPOTENSION SPINAL ANESHTESIA

Contacts and locations

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Locations

SBÜ Gazi Yaşargil Eğitim ve Araştırma Hastanesi

Diyarbakır, 21070, Turkey (Türkiye)

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