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127005 trials found · Page 6245 of 6351
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Cancer biobank study aims to unlock secrets of immunotherapy resistance
Knowledge-focused CancelledThe goal of this observational study is to examine genetic changes that may contribute to immunotherapy resistance in gastroesophageal cancer. This information can potentially lead to the identification of new immunotherapeutic targets as well as improve the ability to identify t…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Researchers measure breathing, strength, and quality of life in hospitalized endocrine patients
Knowledge-focused CompletedThe aim of this observational study was to examine the clinical and functional characteristics of patients hospitalized in the endocrinology department of a university hospital. In line with this purpose, the following research questions were given. What are the respiratory func…
Sponsor: Uşak University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New antifungal drug fosmanogepix tested in healthy volunteers
Knowledge-focused CompletedThe purpose of this study was to investigate the pharmacokinetics and safety of the investigational drug fosmanogepix including its active moiety manogepix following a single dose and multiple doses (by intravenous infusion (IV) or orally) in healthy Chinese adults. The study co…
Phase 1 • Sponsor: Basilea Pharmaceutica • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Lozenges put to the taste test: which flavor wins?
Knowledge-focused CompletedThis is a palatability study on 60 healthy adult and 60 healthy children with 5 different aroma of Lozenges. They will keep the lozenge in their mouth (without swallowing, chewing or breaking) for 10 seconds and then they will eject it. Palatability will be evaluated by the study…
Phase 1 • Sponsor: Aziende Chimiche Riunite Angelini Francesco S.p.A • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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French-Language scale for rare nerve disease put to the test
Knowledge-focused OngoingThis is a national, multicentric, prospective, descriptive study evaluating the psychometric properties of the French version PLSFRS scale
Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Can a competition make nursing students waste experts?
Knowledge-focused OngoingThe aim of this study is to investigate the effect of training nursing students on waste management through an educational competition method on their knowledge and satisfaction levels compared to the traditional method. During the training process, students will learn the correc…
Sponsor: SÜMEYYE BİLGİLİ TEKİN • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Can a simple video replace a wearable sensor for gait analysis in seniors?
Knowledge-focused Ongoing-This observational study aims to compare gait analysis performed using pose estimation algorithms with inertial measurement unit (IMU)-based gait analysis in older adults. Additionally, it aims to determine the reliability of gait analysis using pose estimation algorithms in thi…
Sponsor: Bozok University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Postpartum pain trial halted after just 3 women enrolled
Symptom relief Stopped earlyPostpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain. The research hypothesis of this study is that adding a loca…
Phase 4 • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Healthy volunteers test new drug tablet forms
Knowledge-focused Stopped earlyThe main purpose of this study is to compare the bioavailability of 3 different formulations of LY4100511 and if the use of a proton pump inhibitor (PPI) alters the bioavailability of the 3 different formulations.
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Sep 09, 2026 17:00 UTC
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Can a snack-sized app replace full diet tracking?
Knowledge-focused Recruiting nowTo learn if a method of abbreviated food tracking (called MySnackTracker) is a reasonable alternative to traditional full-intake food tracking and to compare the adherence to and acceptability of each method.
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Healthy volunteers test new drug AMG 378 for safety
Knowledge-focused Stopped earlyThe main objective of the study is to assess the safety and tolerability of AMG 378 as single or multiple doses in healthy participants.
Phase 1 • Sponsor: Amgen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Dry teeth lose their glow: study uses special lights to track changes
Knowledge-focused OngoingA cheek retractor will be placed to ensure consistent isolation throughout the procedure. Dehydration will be assessed at baseline, at the 5th minute, and at the 10th minute using three different evaluation techniques. At each time point, digital photographs will be captured unde…
Sponsor: Marmara University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New study tests which retainer makes teeth whitening more comfortable
Symptom relief CompletedThis randomized single-blind, split-mouth clinical trial evaluated patient satisfaction with at-home dental bleaching using orthodontic retainers with different margin designs, as well as bleaching efficacy, tooth sensitivity (TS), and gingival irritation (GI).
Sponsor: Universidad Rey Juan Carlos • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Healthy volunteers help test injection devices for new drug
Knowledge-focused CompletedThe purpose of this study is to compare the pharmacokinetic (PK) exposures of a single subcutaneous (SC) dose of tozorakimab administered using AI or APFS in healthy participants.
Phase 1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New drug LIFE-001 tested in healthy people for first time
Knowledge-focused Recruiting nowThe goal of this clinical trial is to learn if LIFE-001 is safe and tolerable for healthy adult volunteers.
Phase 1 • Sponsor: LifeMine Therapeutics • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Healthy volunteers needed to test experimental Drug's safety
Knowledge-focused PausedPart A: The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 3031185 in healthy male subjects following administration of multiple rising doses. Part B: The main objectives of Part B of this trial are to investigate safety, to…
Phase 1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Healthy volunteers test two versions of Immune-Boosting drug
Knowledge-focused CompletedThe Goal of these study is to assess the comparative pharmacokinetics of Test Product (A): TPI-120 Injection 6 mg/0.6 mL solution in a single dose pre-filled autoinjector, manufactured by Kashiv Biosciences LLC, USA with Reference Product (B): TPI-120 Injection 6 mg/0.6 mL soluti…
Phase 1 • Sponsor: Kashiv BioSciences, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Sourdough science: can fermented bread tame blood sugar?
Knowledge-focused CompletedThe primary intervention for management of prediabetes is lifestyle changes. Eating healthier and increasing physical activity was found to slow the progression of prediabetes into diabetes, reduce the risk of other diseases like cardiovascular disease and hypertension, and have …
Sponsor: Arizona State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Does trust shape your workout? new study investigates
Knowledge-focused By invitation onlyTrust is the willingness of people to cooperate. Although much research has been conducted on physical activity, little research has explored trust in institutions regarding environmental and physical activity recommendations. This study aims to assess the level of trust in sourc…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Healthy volunteers test drug interactions for BGB-16673
Knowledge-focused CompletedThe purpose of this study is to investigate the effect of coadministration of phenytoin or itraconazole on the pharmacokinetics of BGB-16673 in healthy participants.
Phase 1 • Sponsor: BeiGene • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC