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127005 trials found · Page 6187 of 6351
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Radioactive microdose reveals Drug's journey in healthy men
Knowledge-focused OngoingFor this study, the study medicine has been specially prepared to contain radiolabeled carbon \[14C\]. \[14C\] is a naturally occurring radioactive form of the element carbon. Adding a low dose of radiation to the study medicine does not change how the medicine works but helps to…
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Which CoQ10 supplement works better? new study aims to find out.
Knowledge-focused CompletedThe goal of this clinical trial is to compare the relative bioavailability of coenzyme Q10 (CoQ10) from acute administrations of a CoQ10 product designed for enhanced absorption versus a standard CoQ10 product in healthy men and women. Participants will be asked to come to the cl…
Sponsor: Midwest Center for Metabolic and Cardiovascular Research • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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New drug BW-50218 put to first safety test in healthy chinese volunteers
Knowledge-focused OngoingA Phase 1 Study of Single-Dose BW-50218 in Healthy Chinese Participants
Phase 1 • Sponsor: Shanghai Argo Biopharmaceutical Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Healthy volunteers help scientists measure how two drugs enter skin and blood
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate the interstitial concentrations using the open-flow microperfusion device and plasma pharmacokinetics following multiple doses of povorcitinib or topical ruxolitinib cream in healthy adult participants.
Phase 1 • Sponsor: Incyte Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Prostate surgery lung changes under microscope
Knowledge-focused Not yet recruitingThis study aims to evaluate changes in driving pressure and static lung compliance during HoLEP surgery and to investigate their relationship with surgical and perioperative factors. This study is observational, and no changes will be made to the patients' current treatment proce…
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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High-Tech training boosts nursing Students' injection skills
Knowledge-focused CompletedThe aim of this study was to evaluate the impact of a skills training program-conducted using augmented reality (AR) and 3D model technologies-on first-year nursing students' knowledge, skills, anxiety, and satisfaction, as well as the retention of learning, regarding the correct…
Sponsor: Karabuk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New kidney disease drug candidate tested in healthy people for first time in asia
Knowledge-focused Not yet recruitingThis is a first time in Asia (FTIA) study of GSK4771261 in healthy participants of Chinese, Japanese, and White/European ancestry. The study will test whether GSK4771261 is safe, well-tolerated, how it is processed in the body, and whether it triggers an immune response.
Phase 1 • Sponsor: GlaxoSmithKline • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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New drug HS-20136-2 enters first human safety trial
Knowledge-focused Not yet recruitingThis is a randomized, double-blind,placebo-controlled phase I clinical study.The main purpose is to assess the safety and tolerability of single subcutaneous administration of HS-20136-2 injection in healthy participants.
Phase 1 • Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Foam roller showdown: can it beat a real massage?
Knowledge-focused Not yet recruitingObjective: This study aims to compare the effects of two techniques-foam rolling (FR) and therapeutic massage-on reducing the muscle tone in the calf muscles (gastrocnemius and soleus) of healthy individuals. Methods: A randomized, controlled crossover design was used with 40 he…
Sponsor: Universidad Europea de Madrid • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Kinesio tape study aims to uncover muscle secrets
Knowledge-focused Not yet recruitingThe aim of this study is to investigate the effects of kinesio taping applied to the gastrocnemius muscle on muscle oxygenation, pain pressure threshold, and mechanical properties of the muscle in healthy young individuals.
Sponsor: Okan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Lyme disease trial withdrawn before it even started
Disease control CancelledLyme disease is a public health crisis in the US. It is estimated that over 400,000 cases occur every year with 10-20% of those infected going on to develop Post-Treatment Lyme disease Syndrome (PTLDS). The goal of this study is to investigate if giving Ceftriaxone every 5 days f…
Phase 1/2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New enzyme drug tested in healthy volunteers
Knowledge-focused Not yet recruitingThe study is being conducted to evaluate the safety, pharmacokinetics, and immunogenicity of recombinant human hyaluronidase in healthy Chinese adult male subjects.
Phase 1 • Sponsor: Shanghai Henlius Biotech • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Can better instructions make urine collection easier?
Knowledge-focused Recruiting nowThe aim of this study is to improve the instructions for use and to evaluate the usability of a novel first-void urine collection device.
Sponsor: Universiteit Antwerpen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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New COPD drug candidate AN01 begins first human safety tests
Knowledge-focused CompletedAN01 is a selective small-molecule dual inhibitor of phosphodiesterase 3 and 4 (PDE3/4). As a potential new therapy for COPD, AN01 is expected to serve either as a monotherapy for COPD or as adjunctive therapy to current inhaled standard treatments, potentially generating synerg…
Phase 1 • Sponsor: AirNexis Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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Crunch time: study tests if thicker crisps slow down eating
Knowledge-focused Not yet recruitingTo analyse texturally altered crisp products that exhibit variations in hardness and thickness. The aim is to generate knowledge on how these properties influence eating behaviour (number of chews, rate of consumption, etc.), sensory and liking ratings in a fixed-portion laborato…
Sponsor: PepsiCo Global R&D • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Pfizer tests new drug absorption in healthy volunteers
Knowledge-focused Recruiting nowThe purpose of this study is to learn how different forms of the study medicine called PF-08049820 are absorbed and eliminated in healthy adults. The study will assess whether the study medicine is absorbed differently when taken with or without food. It will also assess absorpti…
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New drug NHL907 tested for safety in healthy people
Knowledge-focused Recruiting nowThe goal of this study is to evaluate the safety, tolerability and pharmacokinetics of NHL907 when administered as multiple oral doses in healthy adult participants.
Phase 1 • Sponsor: NeuHyll AUS Pty Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Healthy volunteers help test new drug formulation
Knowledge-focused CompletedThe objective of this study is to evaluate the pharmacokinetics (PK) and relative bioavailability of emraclidine following single oral administration of different immediate-release (IR) tablet formulations in healthy adult participants.
Phase 1 • Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Healthy volunteers test two versions of experimental drug
Knowledge-focused OngoingThis study will compare the pharmacokinetics (PK) effect of two different formulations of Gecacitinib Hydrochloride Tablets in healthy Adult participants
Phase 1 • Sponsor: Suzhou Zelgen Biopharmaceuticals Co.,Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Blood test could spot hidden cancer cells after breast cancer surgery
Knowledge-focused CancelledThis clinical trial studies how well circulating tumor deoxyribonucleic acid (ctDNA) based minimal residual disease (MRD) detection works for patients with early-stage breast cancer. MRD refers to a very small number of tumor cells that remain in the body during or after treatmen…
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC