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127005 trials found · Page 6158 of 6351
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Epidural drugs may affect Baby's heartbeat, study finds
Knowledge-focused Stopped earlyThe aim of the investigators study is to demonstrate the association between fetal cardiac rhythm abnormalies after epidural analgesia and the maternal systemic transfer of ropivacaine and/or sufentanil.
Phase 4 • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Are doctors following heart check rules for arthritis patients?
Knowledge-focused CompletedIntroduction Cardiovascular diseases are the first cause of death in rheumatoid arthritis (RA). In 2010, EULAR Standing Committee for Clinical Affairs provides 10 recommendations for cardiovascular risk management in patients with rheumatoid arthritis, including a cardiovascular …
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Gene study seeks clues to inflammation and disease risk
Knowledge-focused CompletedBackground: \- Research has shown that certain proteins in cells may be linked to higher risks of developing inflammations, tumors, and other medical problems. By examining how the blood cells of healthy volunteers respond to environmental exposures, researchers hope to better u…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Why thigh fat might be better than belly fat: new study
Knowledge-focused CompletedThe purpose of this study is to compare, in healthy women, the adipose tissue composition between abdomen and thigh and then determine whether differences exist independently of the state of obesity. The findings of this study may help to explain the mechanism contributing to a …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:00 UTC
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New scale aims to predict constipation in hospitalized patients
Knowledge-focused CompletedDevelop a risk assessment scale for constipation of hospitalized patients to identify at an early stage high-risk individuals and to implement the appropriate means of prevention.
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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1,000 volunteers help scientists unlock secrets of healthy aging
Knowledge-focused CompletedThe purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional Review Board Pro00011196) to specifically target and enroll 1,000 participants across age groups and other demographic categories in order to develop a diverse cohort with specific physic…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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1200 lung biopsies analyzed: how often do complications occur?
Knowledge-focused CompletedAt St. Olavs Hospital, a prospective collection of data on complications related to CT-guided lung biopsies has been conducted over several years as part of quality control study. The primary aim of this quality control study is to map complications in all patients who have under…
Sponsor: St. Olavs Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Gene link to ICU blood sugar problems found
Knowledge-focused CompletedThis study evaluates the link between genetic polymorphisms as r7903146, rs12255372 of TCF7L2 gene and the risk of developing hyperglycemia during Intensive care unit stay
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Power tool for bone marrow biopsies tested in kids
Knowledge-focused CompletedThe purpose of this study is to compare use of a powered bone marrow aspiration and biopsy device (OnControl) to use of a standard manual bone marrow aspiration and biopsy device to obtain bone marrow biopsy specimens in children. The hypothesis is that use of the powered device …
Sponsor: Vidacare Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New Angle-Measuring tools could make biopsies more accurate
Knowledge-focused CompletedBackground: \- Currently, standard procedures for biopsies that are guided by computed tomography (CT) imaging involve CT scans and a computer program to plan and illustrate where the physician will place the needle to obtain the required cells or tissue. Inserting the biopsy ne…
Phase 1 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Breathing tube removal method may boost oxygen after surgery
Knowledge-focused CompletedThe primary objective is to show that positive pressure extubation improves oxygenation immediately after extubation compared to extubation via "aspiration" by evaluating and comparing the onset time of desaturation during spontaneous ventilation during awakening following genera…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New registry tracks mysterious connective tissue disease to uncover clues
Knowledge-focused Recruiting nowThis registry has been established to gain a better understanding of the clinical and emotional presentations of patients with undifferentiated connective tissue disease.
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Which mattress wins? study tests pressure relief for bedridden patients
Knowledge-focused CompletedThe primary objective of this study is to compare the distribution of pressure among pressure interfaces between two anti-bedsore mattresses.
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Robot help for Surgeons-in-Training: does it speed up learning?
Knowledge-focused CompletedThe primary objective of this study is to compare two groups of gynecologic/urologic/visceral internes in terms of the time required to perform a laparoscopic surgical intervention (nephrectomy) on an animal model (pig). The two groups of internes differ by the type of training …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Alzheimer's gene clue: does CR1 play a role?
Knowledge-focused CompletedMain objective: investigate whether a functional polymorphism of CR1 (length, number of binding sites in C4b C3b, erythrocyte density, rate of soluble CR1 ...) so determined genetic or acquired, is a susceptibility factor for the disease Alzheimer's.
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Emergency room misunderstandings revealed in major study
Knowledge-focused CompletedEvaluation of global understanding and with items of patients admitted to the emergency. Prospective observational study randomized in cluster during 6 weeks in 14 centers
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New MRI techniques aim to reveal Body's hidden secrets
Knowledge-focused Recruiting nowThe purpose of this study is to develop and refine the techniques for using magnetic resonance imaging and magnetic resonance spectroscopy to understand the composition and function of the human body
Sponsor: AdventHealth Translational Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Heart tissue bank aims to unlock secrets of childhood heart disease
Knowledge-focused Recruiting nowThe purpose of this protocol is to redefine the Heart Institute BioRepository (HIBR) to facilitate Investigator-initiated and programmatic basic, translational, clinical and outcomes research. For the purposes of this protocol, "tissue" will refer to any gross specimen obtained f…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Can changing what you say about food improve your Family's health?
Knowledge-focused CompletedExamine the effect of three different dietary messages on dietary intake and the health of parents and their children.
Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Scientists examine which metal plates best fix broken thigh bones near the knee
Knowledge-focused CompletedIn order to assess the rate and mode of failure cases observed in patients with distal femur fractures treated with a distal femur plates, anonymized radiographs from those patients will be collected retrospectively. All available images will reviewed by an expert review board i…
Sponsor: AO Innovation Translation Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:57 UTC