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127005 trials found · Page 6128 of 6351
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New device aims to spot failing breast flaps before it's too late
Knowledge-focused Stopped earlyThe study will evaluate the use of near infrared spectrometry (NIRS)in detecting early microvascular complications in deep inferior epigastric artery perforator (DIEP)-flap(s).
Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Tiny eye movements reveal secrets of Brain's attention network
Knowledge-focused CompletedThis research aims to highlight the key roles of the cerebellar and cortical fronto-parietal networks in the coupling of eye movements with visual perception and visuo-spatial attention.
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:36 UTC
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New sensor aims to take the guesswork out of IV fluids during surgery
Knowledge-focused Stopped earlyThis is a prospective, nonrandomized, sequential data collection study to evaluate the ability of RPVi to predict fluid responsiveness in comparison with other dynamic parameters including stroke volume variation (SVV) and/or pulse pressure variation (PPV).
Sponsor: Masimo Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Choline pill may harm arteries, small study hints
Knowledge-focused CompletedTrimethylamine-N-oxide (TMAO), a metabolite produced by gut microbial metabolism of dietary choline, has recently been causally linked to atherosclerosis in animal models and has been shown to be predictive of cardiovascular disease (CVD) risk in some but not all cohort studies. …
Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Shoulder surgery recovery: steroid trial halted after just 4 patients
Disease control Stopped earlyThis study is about healing after a rotator cuff tear repair procedure. We hope to learn if a biologic medication: Oxandrolone, a synthetic derivative of the human hormone Testosterone (the principal male sex hormone and an anabolic steroid), given for 12 weeks following rotator …
Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Sharper MRI scans on the horizon: new sequences tested in healthy volunteers
Knowledge-focused Recruiting nowMagnetic Resonance Imaging (MRI) performance depends on equipment performance, equipment maintenance and relevance of MRI sequence used. To optimize MRI performance, it's necessary to develop, optimize, test and validate new acquisition sequences for enhanced diagnosis and therap…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Cheaper avastin copycat tested in healthy volunteers
Knowledge-focused CompletedThe purpose of this study is to compare the pharmacokinetics, as well as to evaluate the safety, tolerability and immunogenicity of HD204, US-Avastin and EU-Avastin in healthy male subjects after intravenous administration of a single dose..
Phase 1 • Sponsor: Prestige Biopharma Limited • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Heart safety check for experimental drug MCI-186
Knowledge-focused CompletedTo evaluate the effect of MCI-186 on the QT interval corrected for heart rate using Fridericia's formula (QTcF)
Phase 1 • Sponsor: Shionogi • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Hepatitis c study tests whether a patient registry is possible in vietnam
Knowledge-focused CompletedThe purpose of this study is to evaluate the feasibility of implementing a cohort of patients with Hepatitis C in order to generate a larger cohort for future studies
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New database aims to speed up FMT research for gut infections
Knowledge-focused PausedThe goal of this study is to rapidly identify subjects who are eligible for the Microbiota Enrichment Program (MEP) at Emory in Atlanta, Georgia. This general screening protocol will be used to screen potential subjects for the Emory MEP and will be conducted at the Emory Clinic,…
Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Treadmill study reveals how uphill and downhill running changes Athletes' oxygen use
Knowledge-focused CompletedThe purpose of this study is: i) to determine if maximal oxygen uptake in downhill running is significantly different versus flat or uphill running, and ii) to compare cardiorespiratory and muscle fatigue responses to uphill vs flat and downhill running at similar running velocit…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Dye reveals hidden oxygen trouble in aortic aneurysms
Knowledge-focused CompletedThis is a prospective study designed to determine the safety and value of Hypoxyprobe-1 (pimonidazole hydrochloride (-HCl)) to detect levels of tissue hypoxia in patients presenting with ascending aortic aneurysm.
Phase 1 • Sponsor: Thomas Gleason • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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THC sleep study: frequent vs. rare users under the microscope
Knowledge-focused CompletedThe investigators will test the effects of 10-60mg dronabinol (oral THC) on sleep in non-frequent and frequent cannabis users.
Early phase 1 • Sponsor: Oregon Health and Science University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Brain zapping study seeks to unlock stress secrets
Knowledge-focused CompletedThis academic study investigates how MRI-compatible transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) influences stress regulation and episodic future thinking in healthy volunteers. Participants undergo one MRI session: combining…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Smoking may weaken dental fillings, new study suggests
Knowledge-focused OngoingThe aim of the study was to evaluate the influence of smoking on the clinical performance of a universal adhesive used with different application modes in non-carious cervical lesions.
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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New thickened drink aims to help swallowing patients get nutrients safely
Symptom relief PausedThis study will evaluate the gastrointestinal (GI) tolerance, compliance , acceptability and safety of a ready-to-use oral nutritional supplement drink for patients with dysphagia.
Sponsor: Nutricia UK Ltd • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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800 patients help Fine-Tune surgery outcome questionnaires
Knowledge-focused CompletedPatient-reported outcome measures (PROMs) are currently used for evaluating orthopaedic procedures. Nevertheless, there is no consensus in the different studies, making them difficult to compare . The score mapping (or cross walk) is a statistical model for estimating a score ass…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Teens' emotion mindsets: brain scans reveal surprising effects of a 25-Minute lesson
Knowledge-focused CompletedThe guiding scientific premise for this research is that a growth emotion mindset will promote more adaptive emotion processing than a fixed emotion mindset. Because emotional sensitivity is particularly salient in adolescent girls, we will focus on this group. Using an experimen…
Sponsor: University of Illinois at Urbana-Champaign • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Study simulates ban on cigarette filter holes to see if smokers switch
Knowledge-focused CompletedEarly attempts by the tobacco industry to develop "safer" cigarettes led to the widespread introduction of ventilation holes in cigarette filters; however, this design feature may instead increase smoking-related harm and make cigarettes more palatable. The overall goal of this p…
Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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How much of that cleaner gets inside you? new study tests tracking methods
Knowledge-focused CompletedBackground: \- In a lifetime, a person may encounter tens of thousands of chemicals used as ingredients in the products they buy. It s not easy to measure them because the companies that sell the products don t have to tell the exact chemical ingredients. Researchers want to com…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC