Choline pill may harm arteries, small study hints
NCT ID NCT03646175
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looked at whether taking a choline supplement (1000 mg) the night before affects blood vessel function in 29 healthy adults. Participants took either choline or a placebo, then had their artery function measured. The goal was to see if choline, which raises a gut-related compound called TMAO, could impair vascular health. Results may help understand links between diet and heart disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- choline (dietary supplement)
- What this could lead to
- If it works, this could help explain how choline from diet or supplements might affect heart health.
- What could go wrong
- This is a small, short-term study in healthy people, so results may not apply to everyone or predict long-term effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Virginia Polytechnic and State University
Blacksburg, Virginia, 24060, United States
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