Choline pill may harm arteries, small study hints
NCT ID NCT03646175
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looked at whether taking a choline supplement (1000 mg) the night before affects blood vessel function in 29 healthy adults. Participants took either choline or a placebo, then had their artery function measured. The goal was to see if choline, which raises a gut-related compound called TMAO, could impair vascular health. Results may help understand links between diet and heart disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
choline (dietary supplement)
What this could lead to
If it works, this could help explain how choline from diet or supplements might affect heart health.
What could go wrong
This is a small, short-term study in healthy people, so results may not apply to everyone or predict long-term effects.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Virginia Polytechnic and State University
Blacksburg, Virginia, 24060, United States