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127005 trials found · Page 6118 of 6351
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Vaccine check-up for kids with diabetes
Knowledge-focused CompletedThis is an observational, single-center, cross-sectional study about adherence to both obligatory and recommended vaccination in children with Type 1 Diabetes Mellitus and their siblings.
Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Back pain mystery: scientists map pain types in 150 patients
Knowledge-focused CompletedTo investigate whether different clinical, psychophysical and neurophysiological phenotypes can be identified among low back pain patients
Sponsor: Balgrist University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Gene therapy aimed at cutting opioid use for diabetic nerve pain – but trial never started
Disease control CancelledA double-blind, randomized, placebo-controlled, single-center, 12-month phase 2 study designed to assess the safety and efficacy of VM202 as a replacement for opioid analgesics in opioid-tolerant subjects with painful diabetic peripheral neuropathy (DPN).
Phase 2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Magnetic needle guide tested on dummies for safer IV insertion
Knowledge-focused CompletedReal-time ultrasound guidance for central venous catheter catheterism is recommended in order to reduce complication, in particular for internal jugular site1. Nevertheless, the usefulness of ultrasound guidance for subclavian approach remains controversial, in particular because…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New study seeks better way to spot brain injury effects in kids
Knowledge-focused By invitation onlyDiagnosing and documenting the presence of abnormal change in cognitive functions (such as reasoning abilities) in children over time is of upmost importance when it comes to evaluating the impact of neurological injury, disease, and interventions designed to help improve wellbei…
Sponsor: University of Aberdeen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Simple skin test may reveal if brain shunts are working
Diagnosis CompletedThe purpose of the study is to determine if the ShuntCheck test can correctly identify flow or no flow in a ventriculoperitoneal shunt in patients with pseudotumor cerebri.
Sponsor: University of South Florida • Aim: Diagnosis
Last updated Jun 27, 2026 12:35 UTC
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Shelter wellness program aims to empower trauma survivors
Knowledge-focused Stopped earlyWomen currently residing at an emergency shelter for women and children will participate in group sessions that cover topics that promote physical and emotional well-being through a combination of mindfulness exercises and health promotion activities..
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Heart study reveals hidden link between blood vessels and muscle blockage
Knowledge-focused CompletedLeft ventricular obstruction is an invalidating complication of hypertrophic cardiomyopathies (HCM), and endothelial dysfunction has also been observed in these pathologies. However, the relation between obstruction and endothelial and venous dysfunctions has not been previously …
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Teen brain study reveals how social support shields against stress
Knowledge-focused CompletedThe purpose of this experiment is to determine the mechanisms through which parental buffering of stress physiology in response to social evaluative threat diminishes with pubertal development and whether this diminution of effectiveness extends to social buffering by peers (best…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Pea protein vs. whey: which preserves muscle better during weight loss?
Disease control CompletedA pilot study comparing the effects of pea protein versus whey protein on the preservation of muscle mass and functionality in individuals undertaking a weight loss regimen.
Sponsor: University of Manitoba • Aim: Disease control
Last updated Jun 26, 2026 13:27 UTC
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Tooth-Related sinusitis study halted early – results uncertain
Disease control Stopped earlyThe study will be offered to patients for whom chronic maxillary sinusitis will be diagnosed in the first ENT (ear, nose and throat) consultation. These patients will then be seen in a stomatology consultation to determine whether or not a dental cause is objective
Sponsor: Centre Hospitalier Intercommunal Creteil • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Knee replacement recovery: why some still feel pain
Knowledge-focused CompletedThis observational study aims to better understand how knee pain and knee-specific body perception are related over time after total knee arthroplasty (knee replacement) for knee osteoarthritis. Although most people improve after surgery, some continue to experience ongoing pain.…
Sponsor: Prefectural University of Hiroshima • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Can a lung maneuver reveal fluid needs during surgery?
Knowledge-focused CompletedDynamic preload indices, such as pulse pressure variation (PPV) and stroke volume variation (SVV) are generally accepted as accurate indicator of fluid responsiveness in mechanically ventilated patients. Because SVV and PPV are generated by the pressure transmitted from the airwa…
Sponsor: Hallym University Kangnam Sacred Heart Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Which medical adhesive stays put longest without itching? a head-to-head test in healthy women.
Knowledge-focused CompletedThis clinical investigation is a single centre, double blinded, case control study in healthy adult females. This study will be conducted in private rooms at Gentofte Hospital (Hjerte-medicinsk Forskning, post 835, Kildegårdsvej 28, 2900 Hellerup). The investigation centre will …
Sponsor: Ambu A/S • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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New study seeks clues to kidney disease in young adults
Knowledge-focused Recruiting nowThe purpose of this study is to characterize oxidative stress and the Nrf2 antioxidant response in early stages of Autosomal Dominant Polycystic Kidney Disease (ADPKD), while identifying candidate biomarkers.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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New imaging technique could let doctors see lung Cancer's inner workings in real time
Knowledge-focused Stopped earlyLung cancer is currently a major health problem in the UK. Despite being one of the most common cancers, lung cancer has a poor prognosis compared to other types of cancer and is the leading cause of cancer death in the world. As opposed to other organs, the lung is highly suscep…
Early phase 1 • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Eye tests may predict dry eye relief from artificial tears
Symptom relief Stopped earlyThis is a single site, prospective, cross-sectional, controlled clinical study on a total of 66 subjects. The subjects are divided into two groups: Hypertonic Saline Non-Responders (33 subjects) and Hypertonic Saline Responders (33 subjects). After completion of questionnaires, t…
Phase 4 • Sponsor: Tufts Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Heart imaging showdown: which window wins for kids?
Knowledge-focused CompletedMost publication are basing RV volumes on images acquired from the apical window. However, some data have called the practice of basing these images on apical window into question. Moreover, despite our best efforts, we have been unable, in our laboratory to reliably visualize RV…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Sleep apnea machine tested for IPF lung health – but study stopped early
Knowledge-focused Stopped earlyThis study will evaluate the effect of CPAP therapy on esophageal pH and lung inflammation in patients with idiopathic pulmonary fibrosis (IPF) and sleep apnea.
Sponsor: University of Arizona • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Brain scans reveal how stress from low blood sugar rewires neural networks
Knowledge-focused CompletedThe purpose of this study is to examine the effect of a moderately low blood sugar stress on the nervous system. The investigators hope that information obtained from completing this study will help to reveal information about how a non-psychological stress impacts the parts of t…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC