Eye tests may predict dry eye relief from artificial tears

NCT ID NCT04125134

Terminated Symptom relief Sponsor: Tufts Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study aimed to see if certain eye tests could predict which people with dry eye disease would get relief from over-the-counter artificial tears. Researchers planned to enroll 66 adults with dry eye, but the study was terminated early with only 36 participants. Participants used preservative-free lubricant eye drops twice daily for 4 weeks and completed symptom questionnaires and eye exams.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Preservative-free artificial tears (lubricant eye drops)
What this could lead to: If successful, this could help doctors predict which dry eye patients will respond best to artificial tears, leading to more personalized treatment.
What could go wrong: The study was terminated early with only 36 participants, so results are limited and may not be reliable. It is a small, single-site trial with no clear outcome yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE

Contacts and locations

Locations

Tufts Medical Center-New England Eye Center

Boston, Massachusetts, 02111, United States

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Other studies related to the condition(s) this trial covers.