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127005 trials found · Page 6069 of 6351
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Weight loss showdown: surgery vs diet before knee or hip replacement
Disease control Stopped earlyThis is a randomized clinical trial (RCT) to assess the efficacy of bariatric surgery vs medical weight loss vs. the "usual standard of care" to optimize a morbidly obese patient with end-stage osteoarthritis of the hip or knee joint for total joint arthroplasty (TJA). The study…
Sponsor: Boston Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New tool measures the Real-Life impact of vaginal aging in portuguese women
Knowledge-focused CompletedTo determine the reliability and validity of the Portuguese version of the DIVA questionnaire in Portuguese women. This validation will support its use both in research and in routine clinical practice in this population.
Sponsor: Instituto Politécnico de Leiria • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Power nap study: 25 minutes to sharper focus and less stress?
Knowledge-focused CompletedThis protocol aims to investigate the effects of a 25-minute nap on various cognitive variables, such as, simple and selective reaction time, stress and the detection and management of disruptive behaviors during instructional activities.
Sponsor: Higher Institute of Sport and Physical Education, Ksar-Said • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Doctors test which score best predicts lung disease survival
Knowledge-focused CompletedThe goal of this retrospective observational study is to evaluate and compare the prognostic value of GAP, ILD-GAP, and CPI scoring systems in patients diagnosed with interstitial lung diseases (ILDs), specifically Idiopathic Pulmonary Fibrosis (IPF), fibrotic Hypersensitivity Pn…
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:07 UTC
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Web tool boosts nursing Students' drug calculation skills
Knowledge-focused Recruiting nowThis study is a randomized controlled trial that aimed to investigate the effect of a web-supported interactive learning program on the knowledge level of nursing students about pediatric drug dose calculation. The study was conducted at one of Turkey's most established nursing …
Sponsor: Ege University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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VR meditation study aims to ease pain and stress – but was pulled
Symptom relief CancelledThis is an exploratory study investigating the use of virtual reality-based guided mindfulness meditation in improving pain, stress, and mood within various clinical populations. The feasibility of utilizing VR applications within the populations of patients with various specific…
Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can a DIY app replace the eye chart? new study puts it to the test
Diagnosis CompletedThis study aims to verify the accuracy of a new Digital Visual Acuity test. The test results obtained with the support of the device will be compared to the current standard of care related to visual acuity testing.
Sponsor: Ojenforeningen • Aim: Diagnosis
Last updated Jun 27, 2026 08:10 UTC
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Italian diabetes heart risk under the microscope
Knowledge-focused Recruiting nowCardioMET is an observational, multicenter, real-life registry, intending to collect data on patients with Type 2 Diabetes Mellitus, attending internal medicine and cardiology outpatient clinics. The aim of the registry is to characterize the cardiovascular risk profile and pharm…
Sponsor: Federico II University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New drink aims to help malnourished patients – but will they like it?
Disease control OngoingTo evaluate the tolerance (gastrointestinal) and acceptability of a new Oral Nutrition Supplement in patients with or at risk of disease related malnutrition.
Sponsor: Aymes International Limited • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Video games and veggies: new program aims to boost teen Well-Being
Knowledge-focused CompletedThe goal of this feasibility study is to learn how to best evaluate the eHOOD intervention of-fered to adolescents in lower secondary education with psycho-social challenges. The main questions it aims to answer are: 1. What is an appropriate evaluation design for testing the eH…
Sponsor: Center for Clinical Research and Prevention • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Bug burgers for biceps? insect protein put to the muscle test
Knowledge-focused CompletedThe purpose of this study is to determine the ability of insect-derived protein supplements (IPC80 and Whole Buffalo Powder Ynsect®) to activate the mTORC1 pathway and protein synthesis in muscle cells. To achieve this aim, participants will consume a supplemental dose (0.25 g/k…
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Which breathing method boosts oxygen best before anesthesia?
Knowledge-focused CompletedThe purpose of this study is to compare the preoxygenation efficacy of tidal volume breathing and vital capacity breathing.
Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Kids' laxative study reveals how body handles the drug
Knowledge-focused CompletedThe primary objective is to measure levels of selected PEG 3350 components and metabolites in the blood and urine of children who are already taking PEG 3350 compared to children who are not taking PEG 3350. Changes to medical therapy are not recommended as part of this study.
Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Teens with hypertension: what keeps them from being active?
Knowledge-focused CompletedOne of the most prevalent chronic disorders in children, especially teenagers, is hypertension . The prevalence of hypertension has significantly increased in recent years, particularly with the rise in obesity. It has been demonstrated that hypertension is a significant, control…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Blood cell counts may reveal clues about autoimmune diseases
Knowledge-focused CompletedPrimary Gougerot-Sjögren's syndrome is a systemic autoimmune disease belonging to the group of connectivities, whose physiopathology remains largely unknown. Quantification and characterization of epithelial and endothelial circulants in Gougerot-Sjögren's syndrome could reflect …
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Promising combo for Hard-to-Treat cancers hits early snag
Disease control Stopped earlyThe purpose of this study is to evaluate the efficacy and safety of copanlisib in combination with fulvestrant in advanced hormone receptor-positive (HR+) solid tumors harboring alterations that activate the Phosphatidylinositol-3 kinase (PI3K) pathway.
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Virtual ruler aims to make PICC line placement safer and faster
Knowledge-focused OngoingThe purpose of this study is to assess the utility of an augmented reality virtual ruler during placement of peripherally inserted central catheters.
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:25 UTC
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Rare disease study maps muscle decline in cystinosis patients
Knowledge-focused CompletedThe primary objective of the study is to evaluate the change in motor function of patients with cystinosis. The secondary objectives of the study: * assessment of the respiratory function; * assessment of the muscle function; * assessment of swallowing disorders; * assessment r…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Rural doctor training aims to get patients moving
Knowledge-focused OngoingThe purpose of this voluntary research study is to determine the impact of an ECHO intervention on the likelihood that rural primary care providers (PCP) will refer their physically inactive patients to be more active.
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Kidney patients needed for pain drug study
Knowledge-focused CompletedThe study is being conducted to evaluate the safety and pharmacokinetic characteristics of SHR8554 injection in subjects with renal insufficiency and healthy subjects.
Phase 1 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC