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127005 trials found · Page 6045 of 6351
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New support program aims to help moms after preterm birth
Knowledge-focused CompletedThis study continues an adaptation of the behavioral intervention Care Coordination After Preterm Birth (CCAPB). This is a pragmatic pilot randomized controlled feasibility trial of CCAPB with baseline and post-intervention assessments.
Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Teen stress study reveals how parents and friends calm the brain
Knowledge-focused CompletedThe purpose of this experiment is to determine the mechanisms through which parental buffering of stress physiology during affective stimulus presentation diminishes with pubertal development and whether this diminution of effectiveness extends to social buffering by peers (best …
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Can online birth classes calm fears as well as In-Person ones?
Knowledge-focused CompletedObjective: The aim of this research study is to evaluate the fear of childbirth, birth beliefs, and mode of birth preferences in pregnant who participated in face-to-face and online childbirth preparation classes. Method: This research is a quasi-experimental study. Pregnant wil…
Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Jumping knee injury study reveals hidden movement differences
Knowledge-focused CompletedPatellar tendinopathy (PT) is a common overuse injury in sports that involve jumping and directional changes. The biomechanical differences between individuals with PT and healthy controls during side-cutting, as well as whether both legs are similarly affected, remain unclear. T…
Sponsor: Peking University Third Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Kidney health may change how this drug works
Knowledge-focused CompletedThe main purpose of this study is to assess the amount of study drug (LY3502970) that reaches the bloodstream and the time it takes for the body to get rid of it when given to participants with renal (kidney) impairment compared to participants with normal renal function. The saf…
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Parent coping skills may shape how children handle cancer, new study suggests
Knowledge-focused Recruiting nowCancer can be a traumatic and particularly salient experience in a person's history. The ways in which the pediatric patient copes with it depend on the interaction of several factors present in his or her life context, primarily the relationship that is established between paren…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Lost in translation: study reveals gaps in hospital discharge for spanish speakers
Knowledge-focused CompletedThe overall goal of this proposed study is to characterize the experiences, barriers and facilitators related to providing effective care transitions from hospital to post-acute care settings to elucidate the failures that drive disparate outcomes using qualitative methodology an…
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Scientists test portable brain scanner to see how blood flow changes
Knowledge-focused Recruiting nowThe investigators propose to employ advanced multi-channel near non-invasive near infrared spectroscopy (NIRS) system married with entirely non-invasive continuous arterial blood pressure (niABP) monitor to create a new wearable and portable imaging system that derives CA maps of…
Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Small study probes genetic roots of Alcohol-Fueled aggression
Knowledge-focused CompletedThis study examines the genetic factors that impact cognitive processes and behavior after alcohol consumption. Participation in this project will contribute to a better understanding of cognitive factors that influence alcohol misuse.
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New drug SHR-2106 tested in healthy volunteers – no cure yet
Knowledge-focused CompletedThis is a randomized, double-blind, placebo-controlled phase I clinical study with the primary objective of evaluating the safety and tolerability of SHR-2106 in healthy subjects after a single intravenous or subcutaneous administration.
Phase 1 • Sponsor: Guangdong Hengrui Pharmaceutical Co., Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Knee replacement patients: do your pain catheters stay put?
Knowledge-focused OngoingThe goal of this observational study is to determine the incidence of dislodgement for adductor canal catheters after total knee arthroplasty on post-operative day 1. We will also attempt to identify factors associated with secondary catheter failure.
Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:29 UTC
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Liver study tracks antibiotic levels in Fluid-Filled bellies
Knowledge-focused CompletedThe investigators designed an observational multicenter explorative in vivo study to investigate the changes in ceftriaxone pharmacokinetics in blood and ascites. The investigators will include a total of 20 patients with liver cirrhosis admitted to the ward of participating hosp…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Pupil dilation may reveal secrets of hearing nerve
Knowledge-focused By invitation onlyThe research team will evaluate pupillary dilation from vagal nerve stimulation of Arnold's Nerve, a branch of the vagus nerve, during routine cochlear implantation surgery.
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Side-Lying pelvic exam could ease patient anxiety
Knowledge-focused CompletedThe gynaecological examination consists of a breast examination, abdominal examination, inspection of the vulva, vaginal touch and pelvic examination with a speculum. The latter is essential for the insertion and removal of intrauterine devices (IUDs), for the diagnosis and scre…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Dental implant study tests new connector to save bone and gums
Knowledge-focused PausedIn dental implant restoration, available literature demonstrates the advantage of using tall abutments, with a change of diameter with respect to the implant and a conical internal connection in the abutment-implant gap. However, for multiple restorations, the abutment-prosthesis…
Sponsor: Universidad de Granada • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Which wire shape moves teeth faster? study compares round vs rectangular archwires
Knowledge-focused CompletedPatients at the Orthodontic Department of the University of Damascus Dental School will be examined, and subjects who meet the inclusion criteria will be included. Then, initial diagnostic records (diagnostic gypsum models, internal and external oral photographs, and radiographic…
Sponsor: Damascus University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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New MRI scan could reveal hidden acidity in prostate tumors
Knowledge-focused OngoingThis is a single site, prospective pilot study to determine the feasibility and safety of the administration of HP 13C bicarbonate in 10 patients with prostate cancer to determine potential hydrogen (pH) values in surrounding tissue. The proposed study will evaluate pre-surgical …
Early phase 1 • Sponsor: Robert Flavell, MD, PhD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New ultrasound software could simplify fatty liver diagnosis
Diagnosis CompletedNon-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, with an estimated prevalence of 5-30% in the general population and 55-80% in patients with type 2 diabetes. Methods for the quantitative and non-invasive assessment of liver fat conten…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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Eye fluid analysis may unlock secrets of rare eye condition
Knowledge-focused OngoingDetermination of proteins and their levels in the vitreous of eyes with or without pseudoexfoliation syndrome (PEX)
Sponsor: Prim. Prof. Dr. Oliver Findl, MBA • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New device maps cervix stiffness to predict preterm birth risk
Knowledge-focused CompletedThe assessment of cervical stiffness plays a major role in obstetrics, for example to assess the risk of preterm birth. The Pregnolia System is a CE-certified measuring device that objectively determines cervical stiffness using a slight negative pressure. The Pregnolia System w…
Sponsor: Pregnolia AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC