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127005 trials found · Page 6015 of 6351
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CAR T-Cell therapy trial for lymphoma pulled before it started
Disease control CancelledThe purpose of this study is to evaluate the efficacy and safety of Liso-cel compared to standard of care in adults with Relapsed or Refractory Follicular Lymphoma.
Phase 3 • Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Experimental antibody IC14 tested in rare heart condition
Disease control CompletedThe goal of this clinical trial is to test IC14 (atibuclimab) in patients with arrhythmogenic cardiomyopathy (ACM) and who have an implantable cardoverter/defibrillator in place. ACM is also called arrhythmogenic right ventricular dysplasia (ARV) or arrhythmogenic right ventricul…
Phase 1/2 • Sponsor: Implicit Bioscience • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Back crack secrets revealed: study probes muscle effects
Knowledge-focused CompletedIn this study, the investigators will examine the effect of manual therapy on the thoracic spine and its impact on the muscular strength gain of the thoracic extensors. Treatment with manual therapy, as described by Maitland, consists of a specific mobilization of the thoracic sp…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Healthy men test new allergy drug copycat in Early-Stage trial
Knowledge-focused CompletedA phase 1, randomized, double-blind, parallel group, single-dose study to compare the pharmacokinetics, safety and immunogenicity of two formulations of Omalizumab (Process-Changed CMAB007 and Xolair) in healthy subjects.
Phase 1 • Sponsor: Taizhou Mabtech Pharmaceutical Co.,Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Can a heart drug combo help COPD lungs?
Knowledge-focused CompletedThis is a 6 week crossover study in current and former smokers with and without COPD to evaluate whether 2 weeks of dual antiplatelet therapy (aspirin 81mg and clopidogrel 75mg) improves pulmonary perfusion (i.e. blood flow in the lungs measured on a contrast CT scan) compared to…
Phase 2 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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New study checks how much MS drug gets into breast milk
Knowledge-focused Recruiting nowThe primary objective of the lactation study is to characterize the presence and concentration of BRIUMVI™ in breast milk among breastfeeding participants who receive BRIUMVI™ therapeutically for the treatment of relapsing forms of multiple sclerosis (RMS).
Sponsor: TG Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Parents share thoughts on limb lengthening device for kids
Knowledge-focused By invitation onlyThe Sponsor is conducting a survey to understand how parents or legal guardians feel about the benefits of using the Precice IMLL System to lengthen limbs in children who are 12 years old or younger.
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Tiny study checks heart drug safety in india
Disease control CompletedThe purpose of this study is to learn about the safety of Tafamidis for the treatment of Transthyretin amyloid cardiomyopathy (ATTR-CM) in India. ATTR-CM is a condition that affects people's hearts. Transthyretin is a protein that is made in the liver. In some people this protei…
Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Oxygen technique during throat surgery may impact heart function
Knowledge-focused CompletedDuring apnoeic oxygenation there is a continuous raise in carbon dioxide with subsequent respiratory acidosis. The hypercapnia and respiratory acidosis have several dose-related effects on both the systemic and the pulmonary circulation and the heart that ultimately, if unrecogni…
Sponsor: Region Stockholm • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Can a smartphone app boost student mental health?
Knowledge-focused CompletedParticipants will take part in a 4-week study consisting of two in-person sessions. During the first session, participants will complete a demographic form and baseline questionnaire, after which the study application will be installed on their preferred device. A research team m…
Sponsor: Nanyang Technological University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Could a forearm shot of naloxone save more lives?
Knowledge-focused CompletedWHAT IS THE PURPOSE OF THIS RESEARCH STUDY This research study is designed to demonstrate that intramuscular (IM) Injection of FDA Approved Naloxone Hydrochloride (HCI) given in the forearm muscle is approximately the same as given the injection in the buttocks muscle. STAT Ther…
Phase 1 • Sponsor: STAT Therapeutics Inc • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:21 UTC
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Personalized cancer vaccine trial for rare skin cancer withdrawn before starting
Vaccine CancelledTo find the highest tolerable dose of an mRNA vaccine that can be safely given to patients with cutaneous angiosarcoma
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Vaccine
Last updated Jun 27, 2026 09:04 UTC
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Jigsaw learning boosts nursing Students' critical thinking?
Knowledge-focused CompletedStudies have proven that the Jigsaw learning method, one of the innovative learning methods, is an effective educational learning tool for nursing students. For nursing education to be sufficient to provide students with the modern roles required by the profession, students must …
Sponsor: Duzce University • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Bite balance may keep jawbone strong in denture wearers
Knowledge-focused CompletedAlthough the number of individuals who are edentulous is declining, a sizable fraction still needs a complete denture for their oral rehabilitation.Tooth loss is an issue in public health that determines quality of life since it is linked to socioeconomic, physiological, and psyc…
Sponsor: Badr University • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Can protein timing fix Sleep-Deprived muscles?
Knowledge-focused CompletedThe current study will determine protein nutritional status (MPS and WBPB) in response to military-relevant sleep loss, and whether an even protein nutrition distribution during recovery optimally supports MPS and WBPB. Adults (n=20) will complete a 7d sleep satiated phase (\~7-9…
Sponsor: United States Army Research Institute of Environmental Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can a simple feeding change help sick kids get better nutrition?
Knowledge-focused OngoingBackground Some critically ill children have malnutrition which may worsen while they are in hospital and delay their return home. They can recover faster when they are given tube feedings to improve their nutrition. Unfortunately, in the hospital these feedings are often interru…
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Eye drop study reveals hidden changes in eye bacteria
Knowledge-focused OngoingThe effect of latanoprost with preservatives on the ocular surface microbiome
Sponsor: University of Ioannina • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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First human test of methylone for PTSD begins
Knowledge-focused CompletedThis is an open-label, single, ascending dose study evaluating the PK and safety of methylone in healthy subjects.
Phase 1 • Sponsor: Transcend Therapeutics • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:35 UTC
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Which ventilation mode is kinder to kids' lungs during anesthesia?
Knowledge-focused CompletedGeneral anesthesia is characterized by temporary loss of consciousness and decreased reflex activity without any change in vital functions. It can be performed with intravenous and/or inhalation agents. During general anesthesia, breathing is stopped and respiratory support is pr…
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Which frenum surgery works best? small trial aims to settle the debate
Disease control CompletedThe goal of this randomized clinical trial is to compare frenotomy to frenectomy surgical techniques in the management of high frenum attachment in adults. The main questions it aims to answer are: * Does Frenotomy procedure have a lower relapse rate compared to frenectomy? * Do…
Sponsor: October University for Modern Sciences and Arts • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC