Could a forearm shot of naloxone save more lives?

NCT ID NCT07180420

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether injecting naloxone into the forearm works as well as the standard injection into the buttocks. Twelve healthy volunteers received the forearm injection to measure how the drug behaves in the body. The goal is to make naloxone easier to give quickly during an opioid overdose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
naloxone hydrochloride
What this could lead to
If successful, this could allow faster and easier naloxone administration during an opioid overdose, potentially saving more lives.
What could go wrong
This is a very early, small study in healthy volunteers, not people experiencing an overdose. Results may not translate to real-world emergency use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • JCCT

    Lenexa, Kansas, 66219, United States