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127005 trials found · Page 5999 of 6351
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New diabetes drug put to the test: will it mess with birth control?
Knowledge-focused CompletedThe purpose of the study is to investigate if NNC0519-0130 affects the blood levels of a birth control pill that contains the two hormones ethinylestradiol and levonorgestrel. The study will also look into if NNC0519-0130 affects how fast stomach is emptied. Participants will get…
Phase 1 • Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Brain zapping study halted early: could it have helped heavy drinkers think more flexibly?
Knowledge-focused Stopped earlyThe goal of this study is to learn whether a single non-invasive brain stimulation alpha-transcranial alternating current stimulation (alpha-tACS) session changes measures of excitability in the prefrontal cortex. It will also learn whether these changes predict differences in ha…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New study maps palate changes in kids with Cross-Bite after expander therapy
Knowledge-focused Recruiting nowThe aim of the present study is to assess the changes of palatal morphology among growing patients with different vertical facial growth patterns treated with rapid palatal expander. Thirty-six patients referred to "Policlinico Agostino Gemelli" university hospital will be selec…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:04 UTC
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Personalized nudge boosts doctor dashboard use
Knowledge-focused CompletedThe study seeks to assess the impact of e-mailing specific, targeted, practice-pattern based information ("precision feedback") on provider engagement with a dashboard for a quality process measure (showing stent omission after pre-stented ureteroscopy), compared with generic inf…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Smile or scare? study tests best way to teach kids to brush
Knowledge-focused CompletedIn the present study, children aged 7 to 14 will receive verbal and active (hands-on) oral hygiene education. The education will be delivered in three different formats: Education supported with positive visual aids (images of healthy teeth), Education supported with negative v…
Sponsor: Eskisehir Osmangazi University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:35 UTC
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Manikin study tests safer breathing techniques for emergency ventilation
Knowledge-focused CompletedBackground and Objective Bag-valve-mask (BVM) ventilation is commonly used in emergency airway management, but the positive pressure generated may increase aspiration risk. This prospective, randomized, simulation-based manikin study aimed to assess how airway pressures change du…
Sponsor: Akdeniz University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Sugar substitute allulose tested for Calorie-Burning boost
Knowledge-focused CompletedThe objective of this study is to investigate the dose-response effect of allulose on diet-induced thermogenesis, substrate oxidation, glycemic response, and subjective appetite in healthy normal weight adults.
Sponsor: Toronto Metropolitan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Flexible dentures may beat rigid ones for implant fit
Disease control CompletedThe aim of removable prosthodontics is not only to restore lost oral structures but also to preserve the remaining tissues. Implant-retained overdentures have shown superior outcomes over conventional dentures by reducing residual ridge resorption, enhancing prosthesis support an…
Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Anesthesia alters blood pressure readings: new study on thyroid surgery patients
Knowledge-focused CompletedThe goal of this observational study is to clarify the relationship between upper and lower limb blood pressure in thyroid surgery patients under general anesthesia. The hemodynamic state during anesthesia is different from that during the awake state. Therefore, to assess whethe…
Sponsor: Ilsan Cha hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Baby breathing machine under the microscope: new study watches how it works
Knowledge-focused CompletedThe purpose of this study is to evaluate the safety and performance of High-Frequency Oscillatory Ventilation (HFOV) modes of the Servo-n ventilator in neonates and infants, by using a prospective, observational, single-arm (i.e., non-controlled) and multi-center Post-Market Foll…
Sponsor: Maquet Critical Care AB • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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6,111 women to track breast implant safety over 5 years
Knowledge-focused Recruiting nowThe Mentor Post-Market Clinical Follow-Up Study is a multicenter observational study conducted in China. It aims to collect safety data on Mentor breast implants over a 5-year follow-up period in the Chinese population. In addition to safety data, the study will also gather infor…
Sponsor: Johnson & Johnson Medical (Shanghai) Ltd. • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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Floss or brush? study settles best gum care for retainer wearers
Symptom relief CompletedThis randomized controlled trial aimed to investigate and compare the effects of employing a water flosser versus an interdental brush on the gingival health of individuals with mandibular bonded retainers. The study recognized the significance of oral hygiene for individuals wit…
Sponsor: Aga Khan University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Brain study seeks to uncover why thinking skills keep improving into adulthood
Knowledge-focused Recruiting nowThe Myelex study is a fundamental research study that aims to better understand how the brain functions and develops. The objective of this study is to better understand the role of myelin, a sheath that surrounds nerve fibers and determines the speed of information propagation i…
Sponsor: Centre Hospitalier St Anne • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:53 UTC
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Could potato starch help liver patients think clearly?
Knowledge-focused Recruiting nowThis research is studying how a food product (resistant potato starch) which is a dietary supplement made from potato starch affects the gut bacteria of people with cirrhosis and hepatic encephalopathy. The researchers in this study want to understand how potato starch works in …
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Kids with DCD walk differently when multitasking – new study investigates
Knowledge-focused Recruiting nowThe aim of the study is to collect data in children with developmental coordination disorder (DCD) aged between 7 and 17 years for analyses of the gait pattern while walking at the Gait Real-time Analysis Interactive Lab (GRAIL) at the university hospital of Ghent. Children with…
Sponsor: University Ghent • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Liver study for cancer drug stopped early – only 2 people joined
Knowledge-focused Stopped earlyThe purpose of this study is to evaluate the effect of moderate or severe liver impairment on the drug levels of oral azacitidine and the safety and tolerability of oral azacitidine in participants with myeloid malignancies.
Phase 1 • Sponsor: Bristol-Myers Squibb • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Scientists map a new tendon in the shoulder using ultrasound
Knowledge-focused CompletedThe delto-pectoral tendon (DPT) is a new tendon recently identified. It completes the insertion of the pectoralis major and perfectly explains the different injuries encountered. The objective of this observational study is to visualize this new tendon, the DPT, using ultrasound…
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Doctors under pressure: study gauges muscle strain during delicate cancer removal
Knowledge-focused OngoingThe prevalence of musculoskeletal disorders (MSDs) among endoscopists is estimated between 29 and 89%. The most common disorders are carpal tunnel syndrome, De Quervain tenosynovitis, lateral epicondylitis and neck pain. Factors associated with MSD among gastroenterologists pract…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New gum cleaning method tested for brace wearers: could it be better?
Symptom relief CompletedWhy is this study being done? This study is for people with braces who have gum inflammation (gingivitis), which is when gums are swollen and bleed easily. Braces can make it harder to clean teeth, leading to a build-up of plaque (a sticky layer of germs). The goal is to compar…
Sponsor: King Abdullah University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Bouillon boost: can broth cubes fight vitamin a deficiency?
Knowledge-focused CompletedThe goal of this clinical trial is to measure how well different formulations of vitamin A (VA) are absorbed by the body when they are added to bouillon (broth) as vitamin A palmitate (VAP). Fortifying bouillon cubes with VA is one potential approach to addressing VA deficiency, …
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC