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127005 trials found · Page 5886 of 6351
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Brain chemical booster may unlock secrets of learning
Knowledge-focused Recruiting nowAdministration of low-dose selective noradrenaline reuptake inhibitor (sNRI) (e.g. atomoxetine) to healthy subjects is a validated model of increasing cortical noradrenaline levels which, combined with computational modelling of behaviour, allows fine-grained analysis of the impa…
Sponsor: Centre Hospitalier St Anne • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Liver function and drug processing: a new study
Knowledge-focused Recruiting nowThe purpose of the study is to look at how the body processes a study medicine called vepdegestrant in participants with loss of liver function relative to people with normal liver function. This study is seeking participants who are: * females who cannot have children or males…
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Ketone supplement tested to boost cycling endurance
Symptom relief Not yet recruitingThe goal of this clinical trial is to determine whether a ketone supplement with carbohydrates extends time to fatigue during cycling compared with a carbohydrate-only supplement in healthy, trained cyclists aged 18-55. The main questions it aims to answer are: Is the time to fa…
Early phase 1 • Sponsor: University of Oklahoma • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Researchers watch how toddlers use screens at home
Knowledge-focused Recruiting nowThis study aims to explore the context of how children aged 3-5 use interactive electronic devices like tablets or smartphones in their everyday home environment. The researchers will look at the social, family, and environmental factors that shape this use. This study will use …
Sponsor: Sheffield Hallam University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Massage gun science: can percussive therapy reshape your muscles?
Knowledge-focused Recruiting nowPercussive massage therapy (PMT) is widely used in therapeutic and athletic settings, but its effects on muscle architecture are not yet fully understood. This study aims to examine the acute effects of PMT applied to the plantar flexor muscles on the muscle architecture of the m…
Sponsor: Karadeniz Technical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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New drug safety check: how does JP-1366 mix with heart meds?
Knowledge-focused Recruiting nowto Evaluate the Safety and the Pharmacokinetic and Pharmacodynamic Interactions between JP-1366 and Clopidogrel, Aspirin, Atorvastatin and Apixaban
Phase 1 • Sponsor: Onconic Therapeutics Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Eczema registry aims to map Real-World treatment journeys
Knowledge-focused Recruiting nowThe objectives of this prospective non-interventional study are to characterize the existing unmet needs across the spectrum of atopic dermatitis (AD), enhance the understanding of the patient journey, and evaluate the safety and clinical outcomes of systemic AD treatments in a r…
Sponsor: Sanofi • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
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Brain scans reveal Stress's hidden impact
Knowledge-focused OngoingThe purpose of this study is to examine whether experiencing a social stressor prior to the collection of neuroimaging measures is associated with differences in brain activation in healthy participants.
Sponsor: Massachusetts Institute of Technology • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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New tool aims to better measure hand burn healing in turkish patients
Knowledge-focused Recruiting nowThe goal of this observational study is to evaluate the validity and reliability of the Turkish adaptation of the Burnt Hand Outcome Tool (BHOT) in adults with a history of hand burns. The participant population will include adults aged 18 years and older who have experienced uni…
Sponsor: Necmettin Erbakan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Slow-Release protein study aims to boost nutrients for half a day
Knowledge-focused OngoingThe overall goal of this study is to determine the minimum dose required to elicit measurable elevation of plasma essential amino acid levels 12 hours after consuming VitaKey's extended release protein technology. The results of this study will be used to set a dose for future pr…
Sponsor: VitaKey Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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App encourages legume purchases in new study
Knowledge-focused CompletedThis study aims to evaluate the efficacy of a healthy diet promotion intervention focused on increasing legume consumption. The intervention is delivered via mobile application in a sample drawn from the healthy adult population.
Sponsor: University of Milano Bicocca • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Can custom workouts boost fitness in native american youth?
Knowledge-focused Not yet recruitingThis longitudinal study will investigate effects of exercise participation in Southwest Native American adolescents, ages 11-17, from the Gila River Indian Community. Vital signs, physical activity participation adherence, physical performance measures, and psychological/social m…
Sponsor: Midwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Improv classes for surgeons: a new way to sharpen the mind?
Knowledge-focused OngoingThis study offers improvisation training for otolaryngology residents to see if there is any impact on connection, stress, and mood. A control group of otolaryngology residents continues their standard medical education with no improvisation.
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New injection for high cholesterol begins first human safety tests
Disease control Recruiting nowThis is a randomized, double-blind, placebo-controlled, single ascending dose (SAD) study of SYH2070 injection when administered subcutaneously to healthy subjects.
Phase 1 • Sponsor: CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Heat pads vs. massage guns: which soothes a tight jaw best?
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate the changes in the stiffness of the masseter muscle (a jaw muscle) before and after two types of treatment: applying commercial heat pads or using a commercial massage gun. We will measure the muscle stiffness on the surface of the muscle…
Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Sleep secrets after nose surgery: Anesthesia's surprising role revealed
Knowledge-focused CompletedThis prospective observational study aims to evaluate the relationship between anesthesia type and postoperative sleep quality in adult patients undergoing septoplasty. Patients will receive either total intravenous anesthesia or inhalational anesthesia as part of routine clinica…
Sponsor: Sevim Şenol Karataş • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Table tennis showdown: which HIIT workout boosts performance best?
Knowledge-focused CompletedThis study aims to investigate the effects of two different Tabata-based high-intensity interval training (HIIT) modalities on neuromuscular and physiological performance in competitive table tennis players. Participants will be randomly assigned to either a calisthenic/plyometri…
Sponsor: Karabuk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Game on for safer medicine: study tests kahoot! to train future nurses
Knowledge-focused CompletedThis study aims to evaluate the effectiveness of gamification (using interactive tools like Kahoot!) on nursing students' awareness and knowledge levels regarding medication safety. Medication errors are a significant concern in healthcare, and innovative educational methods are …
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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What worries you before surgery? researchers want to know
Knowledge-focused Recruiting nowThis study wants to obtain more information regarding the patient's concerns since concerns of the patient about the procedure is found as a predictor for the development of chronic post-surgical pain. This step is crucial in translating early identification of a high-risk popula…
Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Dental implant study tracks jawbone health over time
Knowledge-focused CompletedThis retrospective longitudinal observational study evaluates mandibular radiomorphometric indices in patients rehabilitated with different implant-supported prosthetic restorations. Clinical and panoramic radiographic records of adult patients with dental implants were retrospec…
Sponsor: Abant Izzet Baysal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC