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116076 trials found · Page 5716 of 5804
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Knee gel injection trial pulled before it began
Symptom relief TerminatedThe goal of this clinical study is to learn if Hydrogel OA 2% injection is safe and whether it works to improve symptoms of diagnosed knee osteoarthritis in adults when compared to Hyaluronic Acid (Durolane), a treatment that is currently often used for treatment of knee osteoart…
Phase: NA • Sponsor: Allegro NV/SA • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Antibiotics for early water break study halted before start
Knowledge-focused TerminatedThe purpose of this study is to see if the use of prophylactic antibiotics in the expectant management of PPROM less than 22 weeks significantly reduce the rate of delivery within 7 days and to see if the use of prophylactic antibiotics in the expectant management of PPROM betwee…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Depression brain study withdrawn before it began
Knowledge-focused TerminatedIn this project, we will A) track the functioning of a collection of potential neurobiological targets for depression over time, B) examine how fluctuations in the functioning of those targets relates to real-world functioning, and C) in a subset of the sample, determine how the …
Phase: PHASE1, PHASE2 • Sponsor: Jay Fournier • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Menopause may weaken bladder and lungs, study hints
Knowledge-focused CompletedThe aim of this study is to evaluate the relationship between genitourinary system symptoms and respiratory function and respiratory muscle strength in postmenopausal women.
Sponsor: Halic University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New drug LY4268989 tested in healthy people for safety and processing
Knowledge-focused CompletedThe purpose of this study is to measure the body's absorption and processing of the study drug, the study drug's effect on the body, safety, and tolerability with LY4268989 (MORF-57) in healthy participants, including Japanese and Chinese participants
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Biosimilar breast cancer drug trial pulled before it started
Disease control TerminatedThe purpose of this research study is to compare the efficacy and safety of EG1206A with Perjeta in combination with trastuzumab and chemotherapy as neoadjuvant treatment for 18 weeks, followed by surgery and subsequent EG1206A or Perjeta in combination with trastuzumab, as adjuv…
Phase: PHASE3 • Sponsor: EirGenix, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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VR headsets aim to ease OCD brain treatment — but study pulled
Symptom relief TerminatedThis study will focus on the use of Virtual Reality (VR) technology in patients receiving treatment using Transcranial Magnetic Stimulation (TMS) for Obsessive-Compulsive Disorder (OCD)
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Pain relief showdown for broken ribs: IV lidocaine vs nerve block
Symptom relief TerminatedRecently in 2016, a new interfascial plane nerve block was developed for thoracic analgesia known as the erector spinae plane block (ESPB). Since its development for thoracic neuropathic pain, the ESPB has been shown to be effective in pain control in multiple procedures includin…
Phase: PHASE2 • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Brain-Computer interface aimed at boosting attention in kids with epilepsy – but study never started
Symptom relief TerminatedThe goal of this interventional study is to compare if the use of a brain-machine interface (BCI) therapy can improve the symptoms of attentional deficit by producing brain changes in the networks that modulate attention. The investigators intend to work with epileptic participan…
Phase: NA • Sponsor: University of Texas at Austin • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Prostate cancer study pulled before it began
Knowledge-focused TerminatedThis is an open-label, multicenter, interventional study in racially self-identified black or ethnically self-identified hispanic and racially self-identified white or native American participants with metastatic castration-resistant prostate cancer whose tumors demonstrate molec…
Phase: PHASE2 • Sponsor: Latin American Cooperative Oncology Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Heart failure drug trial pulled before it even started
Disease control TerminatedThe primary objective of the study is to compare relative changes in blood N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels after 30 days of treatment in participants with worsening heart failure (WHF), who are treated with either OPC-131461 or placebo.
Phase: PHASE2 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Healthy volunteers test drug interaction in Early-Stage trial
Knowledge-focused CompletedThe main objective of this trial is to investigate the effect of erythromycin, a moderate CYP3A4 inhibitor on the pharmacokinetics of BI 1291583 at steady state.
Phase: PHASE1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:23 UTC
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Did doctors get the memo? study checks depakine safety alerts in saudi arabia
Knowledge-focused CompletedA cross-sectional, national, multicenter, survey-based study to assess the effectiveness of Risk Minimization Measures related to Depakine® (sodium valproate) in Saudi Arabia. The end of study is defined as the end of the data collection period. No intervention will be administer…
Sponsor: Sanofi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New drug SR750 tested in healthy volunteers – no cure expected
Knowledge-focused CompletedThis is a randomized, double-blind, placebo-controlled phase I bridging study to evaluate the PK, safety and tolerability of SR750 (formulation F1) in Chinese healthy subjects.
Phase: PHASE1 • Sponsor: Shanghai SIMR Biotechnology Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Can a 'Fishbowl' classroom activity boost nursing skills?
Knowledge-focused CompletedBackground: Breathing and coughing exercises are fundamental components of nursing care in the management of chronic respiratory diseases, and the way students learn these skills is closely related to their clinical skill development. Active learning approaches that combine obse…
Phase: NA • Sponsor: Zeynep Yılmaz • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can a drink trick your appetite hormones? small study investigates
Knowledge-focused CompletedThe primary objective of this study is to evaluate post-meal appetite hormones and appetite ratings, assessed using visual analog scale (VAS) questionnaires, in response to proprietary beverages in generally healthy adults.
Phase: NA • Sponsor: Shaklee Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New drug UCB0022 tested for safety in healthy people
Knowledge-focused CompletedThe primary purpose of this study is to assess the safety and tolerability of oral glovadalen (UCB0022) in healthy Caucasian, Japanese, and Chinese participants.
Phase: PHASE1 • Sponsor: UCB Biopharma SRL • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Kidney health may change how body handles experimental drug ESK-001
Knowledge-focused CompletedThis a phase 1, open label, single dose, parallel cohort study to determine the pharmacokinetics (PK) of study drug (ESK-001) in healthy volunteer participants, and participants with mild, moderate, and severe renal impairment.
Phase: PHASE1 • Sponsor: Alumis Inc • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New muscle relaxant injection passes first safety check in healthy volunteers
Knowledge-focused CompletedThis is a single-center, open-label and dose-escalation study to evaluate the safety, tolerability and dose-response relationship of HRS-9190 in healthy adults.
Phase: PHASE1 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Healthy volunteers test new immune globulin injection method
Knowledge-focused CompletedThe main aim of this study is to check how well healthy adults can tolerate TAK-881 with different dosing schedules. During the study, participants will receive one infusion of TAK-881 under the skin (subcutaneous \[SC\] infusion) on Day 1 at a lower dose level followed by parti…
Phase: PHASE1 • Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC