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127005 trials found · Page 5697 of 6351
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New study aims to better detect depression in older adults with cancer
Knowledge-focused OngoingThe purpose of this study is to develop an accurate and useful way of measuring older patients' moods and reactions to the combined issue of cancer treatment and aging. Also, the purpose of this study is to test a new self-report measure of depressive symptoms tailored to the nee…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Plastic bag trick may protect tiny babies from dangerous chills
Prevention CompletedParticular attention is paid to thermal management of preterm neonates in neonatal intensive care units because of the major risk of morbidity associated with hypothermia. Percutaneous central venous catheter placement is essential to ensure adequate caloric intake and intravenou…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Prevention
Last updated Jun 27, 2026 13:08 UTC
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97,000 women join study to see if new IUD prevents pregnancy as expected
Disease control OngoingThis study is designed to investigate whether LCS12 is associated with an increased risk of unintended pregnancy compared to Mirena and to copper IUDs. The objective is to assess among new users the risks of certain events (e.g. contraceptive failure rate, ectopic pregnancy, uter…
Sponsor: Center for Epidemiology and Health Research, Germany • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Scientists hunt for hidden causes of painful leg ulcers in sickle cell disease
Knowledge-focused CompletedBackground: \- People with sickle cell disease and other blood disorders sometimes get chronic leg ulcers. These are wounds that develop on the skin and don t go away. Current treatments do not work very well, so researchers want to learn more about why the ulcers happen. They w…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Large study looks at how a 25-Gene cancer test affects patients and families
Knowledge-focused CompletedThis study is about understanding the use of a genetic test (Myriad Genetics myRisk panel) that analyzes 25 genes related to different hereditary cancer conditions. The investigators hope to learn more about how this type of genetic test is used clinically. The investigators also…
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Which fibroid treatment is cheapest and safest? new study compares options
Disease control CompletedThis Post Market study is being conducted to compare the direct and indirect cost of three approaches (GFA, myomectomy, and uterine artery embolization) for the treatment of symptomatic uterine fibroids. In addition, data from this study is being used to satisfy the requirements …
Sponsor: Acessa Health, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Decision aids may ease patient uncertainty in hand surgery
Knowledge-focused PausedThe investigators plan a prospective randomized controlled study that compares the treatment decisions made by patients who receive decision aids, as compared to patients treated with usual care and the American Society for Surgery of the Hand brochures. The investigators expect …
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Zapping the brain to stop the shakes: small trial shows promise
Symptom relief CompletedThe purpose of this study is to determine whether transcranial cathodal direct current stimulation (tDCS) delivered over the cerebellum can improve essential tremor.
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Thousands join fight against blindness by sharing their stories
Knowledge-focused Recruiting nowThe My Retina Tracker® Registry is sponsored by the Foundation Fighting Blindness and is for people affected by one of the rare inherited retinal degenerative diseases studied by the Foundation. It is a patient-initiated registry accessible via a secure on-line portal at www.MyRe…
Sponsor: Foundation Fighting Blindness • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Baby formula upgrade: could lactoferrin close the gap with breast milk?
Knowledge-focused CompletedBreast milk is the gold standard of early infant nutrition and breastfed infants have advantages in several short and long term outcomes compared to those formula-fed. The first aim of this study is to evaluate the effect of adding bovine lactoferrin to infant formula. The gener…
Sponsor: Umeå University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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New artery surgery shows promise for leg pain
Disease control CompletedEndarteriectomy is considered as the first line treatment of femoral bifurcation atheromatous lesions. Eversion technique, similar to that used for carotid bifurcation, is safe and possible for the majority of the femoral tripod lesions. The major advantage of the eversion techni…
Sponsor: Hôpital NOVO • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Which epidural catheter works best for Post-Surgery pain?
Symptom relief CompletedThe investigators hypothesize that multi-port thoracic epidural catheters will provide superior pain relief when compared to uniport catheters for post-surgical patients.
Sponsor: Beth Israel Deaconess Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Mind tricks for motivation: study tests whether writing essays or making plans can boost studying and exercise.
Knowledge-focused CompletedThe current study aims to investigate two potential interventions (i.e., cognitive dissonance and action planning) for inducing behavior change for behaviors important to college students-studying and exercise. In addition, this study will investigate factors that may impact beha…
Sponsor: Boston University Charles River Campus • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Massive lung disease registry aims to unlock secrets of progressive fibrosis
Knowledge-focused Recruiting nowThe Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) Registry started recruiting in 2014 with the objective of studying Idiopathic Pulmonary Fibrosis. In 2018, the registry expanded to include recruitment of participants with other chronic fibrosing interstitial lung …
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Morphine gel may offer direct relief for chemo mouth sores
Symptom relief Stopped earlyChemotherapy kills tumor cells but can also damage healthy cells and cause significant digestive disorders such as ulcers of the mouth, called mucositis. Mucositis are transient but their intensity may require special measures. Mucositis are painful and morphine gel or intravenou…
Phase 3 • Sponsor: University Hospital, Strasbourg, France • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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ICU patients may need custom doses of common antifungal
Knowledge-focused CompletedInvasive fungal infections (IFIs) are a frequent cause of morbidity and mortality in high-risk patients, such as immunocompromised patients. Candida is currently the predominant fungal pathogen in these patient populations and is associated with significant morbidity and a high m…
Phase 4 • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Spine surgery breakthrough: new nerve monitoring method tested
Knowledge-focused CompletedThough the utility of NVM5 neuromonitoring by stimulating within the surgical site during XLIF has been demonstrated, it is hypothesized that more information may be gathered if a greater section of the motor neural pathway was monitored (i.e., stimulation above the surgical site…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New spinal fluid test may sharpen Alzheimer's diagnosis
Diagnosis CompletedThe combined measurement of Ab42 and tau protein (total and phosphorylated) in the spinal fluid has been shown to be promising in the diagnosis of Alzheimer's disease (AD), and has justified its inclusion new diagnostic criteria. However, it can sometimes yield discordant results…
Sponsor: CHU de Reims • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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Blood test may predict heart attack Patients' future risk
Knowledge-focused CompletedThis prospective study aimed to validate a new prognostic approach of endothelial progenitor cells associated biomarkers in patients with acute coronary syndromes . Recruitment is made prospectively by two centers of Inter -region South Mediterranean,
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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15,000 cancer Patients' data to unlock surgery secrets
Knowledge-focused Recruiting nowThis retrospective study aims at evaluating the outcomes of gastrointestinal stromal tumor after surgery.
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC