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The purpose of this study is to evaluate the pharmacokinetic (PK) similarity of AK112 (an anti-PD-1/VEGF bispecific antibody) from the proposed new manufacturing site and the approved original site in healthy male subjects. Secondary objectives are to assess the safety, tolerabi…

This cross-sectional observational study compared trunk mobility, hamstring flexibility, and dynamic functional balance performance among elite male adolescent athletes aged 15-17 years from different sports branches, including wrestling, sprint athletics, canoe/kayak, and taekwo…

Gut microbiota play a key role in polyphenol metabolism, participating in the breakdown of dietary components and producing various small molecule metabolites that affect human health. However, little is currently known about how gut microbes metabolize dietary compounds and prod…

The purpose of this study is to assess the safety and tolerability of AZD3974 and characterize the pharmacokinetics (PK) of AZD3974 following oral administration to healthy participants, including participants of Japanese and Chinese descent.

The aim of this study is to examine the psychometric properties of the Turkish version of the Scoliosis Caregiver Response and Emotional Scale (SCaRES) questionnaire; to evaluate the reliability of the Turkish form and to ensure its usability in clinical and research fields.

"Artificial intelligence (AI), including large language models and conversational tools, is increasingly being used in medical research. These tools may assist researchers at different stages of the scientific process, such as generating research ideas, reviewing the literature, …

The goal of this observational study is to assess how eating attitudes, sleep attitudes, and perceived stress contribute to early indicators of cardiovascular risk among undergraduate physical therapy students aged 18-30. The main questions it aims to answer are: Do unhealthy ea…

This proposal hypothesizes that mitochondrial bioenergetics in the patient will correspond to mtDNA DAMPs levels and markers of inflammation. We predict these will serve as a prognostic indicator of Sepsis induced cardiac dysfunction (SICD) outcomes. Successful completion of thes…

It aims to objectively reveal the current knowledge levels of surgical physicians, to increase their awareness, and to contribute to in-house training processes with the results obtained and to fill an important gap in the literature.

Background: Children with congenital adrenal hyperplasia (CAH) can survive well into adulthood with proper treatment. But the change from pediatric to adult care can be challenging. Many people with CAH need extra support as they learn to take control of their own health care ne…

The purpose of this study is to examine the effects of simulation training delivered within the framework of the clinical judgment model on nursing students' clinical decision-making skills and perceptions of nursing process competency. The research hypothesis is H1: Simulation t…

The purpose of this study is to gather health and nutrition data from the population of Davis, CA and surrounding areas. This data will be used to help us test and improve our study procedures for a larger planned study on peanut consumption and effects on cardiovascular disease …

The goal of the study is to learn what happens to levels of nemtabrutinib (MK-1026) in a healthy person's body over time. Researchers will compare what happens to nemtabrutinib in the body when it is given with or without another medicine called diltiazem.

The purpose of this study is to evaluate the safety and tolerability of single ascending doses of UCB5285 in healthy study participants, including healthy Japanese study participants

This study plans to learn more about using contrast enhanced ultrasound (CEUS) in brain tumor surgery. The goal of glioma brain tumor surgery is to remove as much of the glioma as possible. Tumor tissue that is close to normal brain tissue can look very similar. This can make it…

This study was conducted as a test-retest investigation to assess the reliability of the methods prior to a planned study on the same topic. Ten volunteer participants were recruited from among employees at Sodersjukhuset (South General Hospital). The radial aspects of the second…

Double Blinded Healthy Volunteer study evaluating D-2570 against placebo in various doses.

Drug-drug interaction study between Ethinyl Estradioll/Levonorgestrel and Bemnifosbuvir/Ruzasvir

The purpose of this study is to determine the absolute bioavailability of SC administered cizutamig in healthy adult participants.

This is a Phase 1, first-in-human, randomized, double-blind, placebo-controlled, single ascending dose, sequential group study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of CAY001 when administered to healthy male and female subjects. Three dose …