Starving the gut: anorexia may damage intestinal barrier
NCT ID NCT02170467
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study checked whether the gut lining becomes leaky in women with anorexia nervosa due to severe starvation. Researchers measured sugar levels in urine after drinking special sugars to test intestinal permeability in 23 patients and compared them to 46 healthy controls. They also looked at certain antibodies and gut bacteria changes before and after refeeding. The goal is to understand how malnutrition affects the gut barrier in anorexia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help explain how starvation affects the gut barrier in anorexia nervosa, potentially guiding future treatments.
What could go wrong
This is a small, observational study with only 23 patients, so results may not apply to everyone. It does not test any treatment.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU- Hôpitaux de Rouen
Rouen, 76031, France
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Hôpital de la Croix Rouge
Bois-Guillaume, 76233, France