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127005 trials found · Page 5620 of 6351
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App game may teach impulsive tots patience
Symptom relief Recruiting nowDeficits in self-control are of major public health relevance as they contribute to several negative outcomes for both individuals and society. For children, developing self-control is a critically important step toward success in academic settings and social relationships, yet t…
Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Blood protein clues may catch malnutrition early in cancer patients
Knowledge-focused CompletedThe purpose of this study is to study the function of pre-albumin, retinol conjugated protein and transferrin in early malnutrition detecting and nutritional status dynamic monitoring for local advanced nasopharyngeal carcinoma patients with chemoradiotherapy.
Sponsor: Zhao Chong • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New test may spot preterm birth risk earlier
Knowledge-focused CompletedPreterm delivery accounts for about 10% of deliveries in France. Prematurity is the leading cause of perinatal morbidity and mortality in economically developed countries. Despite the development of therapeutics and paraclinic examinations, this rate of preterm delivery remains s…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Global XLH registry aims to map the disease's journey from childhood to adulthood
Knowledge-focused Recruiting nowThis is an international, multicentre, prospective, non-interventional, observational Registry of patients with X-Linked hypophosphatemia (XLH). The main objective of this XLH Registry is to collect data to characterise the treatment, progression and long-term outcomes of XLH in …
Sponsor: Kyowa Kirin Pharmaceutical Development Ltd • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Nature sounds may soothe breast biopsy patients
Symptom relief OngoingPatients will be randomly assigned to one of two groups: the group exposed to NS, or the standard care group exposed to supportive dialogue. Patients assigned to the former group will be exposed to continuous NS throughout the CNB procedure.
Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Study reveals why stroke patients skip lifesaving pills
Knowledge-focused CompletedThe effectiveness of emergency management of acute ischemic stroke has improved considerably in recent years with thrombolysis and more recently thrombectomy. This improvement is accompanied by an increase in the number of stroke survivors. One of the major issues for these ever-…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Why are stroke survivors so tired? new study investigates
Knowledge-focused CompletedCerebral infarction is a type of stroke that can lead to sometimes disabling sequelae. Among these sequelae, fatigue is frequently reported by patients. It is therefore important for doctors to understand why patients suffer from fatigue after cerebral infarction and to determine…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Scientists try to peek at blood flow in zero gravity
Knowledge-focused CompletedDuring weightlessness, the cardiovascular system is subject to rapid changes which has been demonstrated in studies of short term (Space Shuttle) and long term missions to Skylab, MIR, and the International Space Station (Nicogossian et al., 1989; Blomquist, 1994; Platts et al., …
Sponsor: University Hospital, Caen • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Scientists use video and sensors to objectively measure apathy
Knowledge-focused CompletedApathy is defined as a quantitative reduction in voluntary and goal-directed behavior. To address this, the investigators propose an ethological approach to assess apathy objectively and quantitatively by observing patients in real-life situations. The ECOCAPTURE paradigm involv…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Eye drops could stop a rare cause of blindness
Disease control CompletedCorneal melt is a complication that could affect very ill eyes and lead to the thinning of the cornea (the clear window covering of the eyes). This thinning can lead to severe consequences such as the leakage of the liquid inside the eye (ocular perforation), or even blindness. C…
Phase 1 • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New cancer drug PM14 enters human testing for advanced tumors
Disease control CompletedDespite recent advances in the treatment of solid tumors in general, advanced (metastatic) disease remains mostly incurable and there is an urgent need to develop new therapeutic options for these patients, particularly investigational drugs with novel mechanisms of action. The i…
Phase 1 • Sponsor: PharmaMar • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Could your phone camera help heal diabetic foot ulcers?
Knowledge-focused Recruiting nowAll study procedures will occur during one appointment. The research team will measure the size of the foot ulcer (if one is present) and multiple photos will be taken with a smart phone camera and thermal camera. Demographic information will be obtained from the medical record.
Sponsor: Linnea Polgreen • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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Can better sleep help kids in the ICU recover faster?
Knowledge-focused CompletedThe study design will allow investigators to describe usual care in each PICU and identify the facilitating and restraining factors impacting the implementation of R2 at each PICU. The purpose of this pilot study is to improve the care, environment, daily routine and sleep patter…
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Which painkiller works best after shoulder surgery? new study compares options
Symptom relief CompletedThis study evaluates the addition of tramadol, or nefopam or opioid to paracetamol and ketoprofene in the treatment of pain in adults after shoulder ambulatory surgery. In a first step, 30 patients will receive tramadol as rescue analgesia in combination with paracetamol and keto…
Phase 4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can eye movements ease Cancer-Related distress? small study tests EMDR in breast cancer patients
Symptom relief CompletedThe study will consist in an adjustment/adaptation of the "standard EMDR protocol" for cancer disease, and most particulary for women who present a breast cancer and during adjuvant therapy. It will also test the faisability of the research, with a view to adjust the calendar and…
Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Blood test may reduce transfusions in severe postpartum bleeding
Knowledge-focused Stopped earlyThe aim of this study is to evaluate the impact of a rotational thromboelastometry (ROTEM®)-based transfusion protocol during postpartum hemorrhage (PPH) after vaginal or cesarean delivery. Maternal transfusion requirement, quantitative blood loss (QBL), need for intensive care u…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Small study aims to perfect antibiotic dosing for kids with cystic fibrosis
Knowledge-focused CompletedThis is an open-label, single center, prospective study of patients with a diagnosis of cystic fibrosis (CF) and a history of methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant Staphylococcus aureus (ORSA), being treated with intravenous ceftaro…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Could a rheumatoid arthritis drug ease knee osteoarthritis pain?
Symptom relief Recruiting nowOsteoarthritis (OA) of knee is the most common form of arthritis in the world1e, and it has received growing attention in the society because of the increase of old age population, disabled people, and medical expenses from this disease. 99Tc-MDP is effective for rheumatoid arthr…
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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New study tracks brain changes after stem cell transplants in seniors
Knowledge-focused CompletedThis study will examine how adults ≥ 60 years old thinking and memory abilities are affected by stem cell transplant; whether these changes affect day-to-day activities and quality of life and how thinking and memory abilities are affected by genetics, depression, anxiety and phy…
Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Veterans try exercise and social events to ease return to civilian life
Symptom relief CompletedOver 2 million soldiers have deployed during the Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) conflicts. While the majority of veterans reintegrate successfully following deployment, a sizable minority return and face difficulties transitioning into civilian…
Sponsor: Jasper A. Smits • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC