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116076 trials found · Page 5583 of 5804
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Study reveals: heart transplant centers that reject more donor hearts seen as worse performers
Knowledge-focused CompletedPublicly available outcome assessments for transplant programs do not make salient that some programs tend to reject many of the hearts they are offered, whereas other programs accept a broader range of donor offers. The investigators use empirical studies to test whether transpl…
Phase: NA • Sponsor: Carnegie Mellon University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Researchers measure heart stiffness during surgery to understand aortic stenosis
Knowledge-focused CompletedElastography is a new non-invasive medical technique for measuring the stiffness at a distance from a tissue. Recent advances in the development of elastography sequences for cardiac exploration suggest a more clinical approach to cardiac elastography. This study propose to compa…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:43 UTC
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3D ultrasound may replace costly scans for kidney patients
Knowledge-focused CompletedThe purpose of this study is to measure the volume of the kidney and tumors using 3D-US acquisition and to correlate these measurements to contrast-enhanced CT or MRI.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Promising myeloma combo trial pulled before it began
Disease control TerminatedThe purpose of this study is to determine the safety, tolerability, and recommended phase 2 dose (RP2D) of TAK-573 when used with dexamethasone and in combination with bortezomib, pomalidomide, or cyclophosphamide, in participants with RRMM.
Phase: PHASE1 • Sponsor: Teva Branded Pharmaceutical Products R&D LLC • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Behçet's disease: hidden mental toll revealed in new study
Knowledge-focused CompletedThe psychoBehçet'study is aimed at evaluating the psychological and neurocognitive symptoms in 25 consecutive patients followed for Behçet's disease. This is a monocentric, observational, non interventional study.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Salt water gargle study for COVID-19 fizzles out early
Symptom relief TerminatedELVIS COVID-19 is a pragmatic web-based Bayesian adaptive randomised controlled, parallel group trial of hypertonic saline nasal irrigation and gargling (HSNIG) compared to standard care in participants with clinically suspected or confirmed COVID-19 being managed at home.
Phase: NA • Sponsor: University of Edinburgh • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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550 COVID-19 patients tracked to learn about the disease
Knowledge-focused CompletedThis is a prospective cohort observational registry study that will include data on all patients who are treated at MHS facilities for COVID-19.
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Protein powder fails to prove recovery boost in tiny hip fracture trial
Symptom relief TerminatedThis randomized, observer-blinded trial tested the hypothesis that nutritional supplementation with muscle-target nutritional supplementation would increase the efficacy of a physical rehabilitation program in old adults with femur fracture treated with surgery.
Phase: NA • Sponsor: Barichella Michela • Aim: Symptom relief
Last updated Jun 26, 2026 13:52 UTC
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Massive data collection aims to spark breakthroughs in blood disorders
Knowledge-focused ENROLLING_BY_INVITATIONBackground: Researchers seek ways to study people s medical problems in order to teach and further general knowledge. The ability to assess and treat people with a wide range of diseases is critical to training people to be good doctors. It is also needed to keep medical staff u…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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Breathing trial showdown: which method helps ICU patients breathe on their own?
Knowledge-focused TerminatedAssessment and comparison of three spontaneous breathing trials in five specific profiles of intensive care unit and perioperative patients. A physiological cross over study
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Heart device registry enrolls 5,000 patients to monitor Real-World outcomes
Knowledge-focused CompletedThis study will provide ongoing, high quality data on the safety, performance, and clinical benefits of Abbott's EP devices in a real-world setting.
Sponsor: Abbott Medical Devices • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Eye drop showdown: which one is gentler on your tears?
Knowledge-focused CompletedThe use of topical anesthesia as well as corneal vital staining with fluorescein is an inevitable part of various ophthalmological examinations and surgical treatments. However, eye drops that don't come in single dose packages are required to contain preservatives such as chlorh…
Phase: PHASE3 • Sponsor: Medical University of Vienna • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Elbow surgery study tracks recovery in over 300 patients
Knowledge-focused CompletedWELBOW study is an international, ambispective and prospective, single arm, multicenter, observational, non-comparative, Post-Market Clinical Follow-up (PMCF).
Sponsor: Stryker Trauma and Extremities • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:38 UTC
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Bone loss in hemophilia: new study measures the hidden risk
Knowledge-focused CompletedHaemophilia is a rare bleeding disorder, characterized by factor VIII (HA) or factor IX (HB) deficiency. The absence or the reduction of fVIII or fIX result in impaired thrombin generation and clot formation, causing excessive bleeding (mainly haemarthrosis). Osteoporosis is a sy…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Cancer drug tested against COVID-19 in small trial
Disease control TerminatedThis study is a randomized Double-Blind Placebo-Controlled Trial on the Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19
Phase: PHASE3 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Super MRI scans reveal hidden spine secrets
Knowledge-focused Recruiting nowHigh-resolution MRI (7 Tesla) of the cervical spine is capable to provide good differentiation between nerve and surrounding tissues within foramen und allows to reliably quantify the diameter of nerve roots/ganglia. Secondly, detailed anatomy of vertebral artery and its relation…
Sponsor: Balgrist University Hospital • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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New iPad tool aims to boost kidney injury awareness in kids
Knowledge-focused Recruiting nowThe purpose of this study is to improve patient-centered care for acute kidney injury (AKI) in order to decrease the adverse health outcomes associated with this common condition.
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Italian MPN patients share their stories in landmark Quality-of-Life study
Knowledge-focused OngoingThis study will ultimately aim at developing a GIMEMA platform for collecting HRQoL and symptom burden information on Italian patients with Philadelphia chromosome negative MPN. The main objective of the protocol is to improve our understanding of the impact of the disease and va…
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Electric field helmet tested for tough brain tumor – but only one patient tried it
Disease control CompletedThis is a Phase 2 study in subjects with WHO Grade III Anaplastic Astrocytoma (G3 astrocytoma) who had progressive disease during first or second line treatment and who have not previously received any BEV or any experimental agents.
Phase: NA • Sponsor: Daniela A. Bota • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Hospital launches COVID-19 data registry to spot death risk factors
Knowledge-focused Recruiting nowSince the start of the COVID-19, Italy, and particularly the Northern region, Lombardia, has initially been the centre of the most numerous reports of confirmed cases of COVID-19 since the spread of the infection to Europe, reaching 5469 cases out of 9172 total cases in Italy (co…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC