Could a simple drug cut blood loss in leg fracture surgery?
NCT ID NCT07261930
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looked at whether giving a single dose of tranexamic acid before surgery can reduce blood loss in adults with broken thigh bones. The trial involved 43 patients in Uganda who had open surgery to fix their fracture. The goal is to see if this common, low-cost drug can lower the need for blood transfusions and improve safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tranexamic acid
- What this could lead to
- If effective, this could provide a simple, low-cost way to reduce bleeding and transfusion needs during femoral fracture surgery in resource-limited settings.
- What could go wrong
- This is a small, completed Phase 4 trial with only 43 participants, so results may not apply broadly. The drug may not significantly reduce blood loss or transfusion needs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mulago National Referral Hospital
Kampala, Uganda
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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