Could a simple drug cut blood loss in leg fracture surgery?
NCT ID NCT07261930
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looked at whether giving a single dose of tranexamic acid before surgery can reduce blood loss in adults with broken thigh bones. The trial involved 43 patients in Uganda who had open surgery to fix their fracture. The goal is to see if this common, low-cost drug can lower the need for blood transfusions and improve safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid
What this could lead to
If effective, this could provide a simple, low-cost way to reduce bleeding and transfusion needs during femoral fracture surgery in resource-limited settings.
What could go wrong
This is a small, completed Phase 4 trial with only 43 participants, so results may not apply broadly. The drug may not significantly reduce blood loss or transfusion needs.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEMORRHAGE, SURGICAL are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Mulago National Referral Hospital
Kampala, Uganda