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116076 trials found · Page 5545 of 5804
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Researchers watch how IBD patients pick their vedolizumab shot or drip
Knowledge-focused CompletedThe primary reason of this study is to observe current treatment options in participants receiving Vedolizumab, intravenous (IV) or subcutaneous (SC), for IBD in Poland. There is no treatment involved in this study, this is only an observational review of ongoing/initiating treat…
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Pre-Surgery workout may boost liver donor recovery
Knowledge-focused Completed1. to determine if a Phase III RCT of prehab vs usual care for LLDs is feasible (including rates of recruitment, adherence, adverse events, and attrition); 2. to determine what, if any, intervention or trial modifications are warranted for a Phase III RCT; and, 3. to explore esti…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New breathing monitor put to the test in healthy volunteers
Knowledge-focused CompletedThe goal of this clinical trial is to compare the performance of a novel non-invasive respiratory monitoring system against the gold standard methods (manual counting) in healthy human subjects. The main question it aims to answer is whether the novel monitoring system comparable…
Sponsor: Michael Chu • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Miami school program aims to boost COVID-19 knowledge and vaccination
Knowledge-focused CompletedThe purpose of this study is to compare COVID-19 knowledge, experiences, and health behaviors between participants who received the health initiative and those who did not.
Phase: NA • Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Which anesthesia is greener? study weighs waste from wrist surgery
Knowledge-focused CompletedFollowing Ethics approval, all adult patients undergoing surgery to fix the wrist fracture will be approached and consent to undergo this study. The amount of waste generated from general anesthetic, regional anesthetic and regional+general anesthetic will be collected and weighe…
Phase: NA • Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Heart attack oxygen boost trial halted early
Disease control TerminatedA multi-center randomized post-approval evaluation of delivery of intracoronary hyperoxemic supersaturated Oxygen therapy for 60 minutes in anterior AMI patients with successful reperfusion (via PCI) within 6 hours after onset of symptoms compared to standard therapy
Phase: NA • Sponsor: TherOx • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Smiley face scale tested for prostate symptoms
Knowledge-focused CompletedINTRODUCTION A simple and repeatable test would be valuable for assessing the severity and impact of urinary symptoms. Visual Analogue Scale (VAS) is a 10 cm line where a participant put a mark in place that describes best his satisfaction with woiding. VAS has been shown to corr…
Phase: NA • Sponsor: Seinajoki Central Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Disposable scope study aims to improve ERCP safety in china
Knowledge-focused TerminatedStudy Objective(s):This study is to evaluate the feasibility, preliminary safety and performance of Exalt D Single-use Duodenoscope in ERCP procedures in China, to generate local real world data from a Chinese ERCP population. Study Design:Prospective, single-arm study Planned N…
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New bone graft shows promise for saving jawbone after tooth loss
Knowledge-focused CompletedRadiographic and Histomorphometric Evaluation of Xenograft as a Socket Preservation Material in Maxillary Posterior Teeth: A Randomized-Controlled Clinical Study
Phase: NA • Sponsor: Suez Canal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Hip fracture hardware under review: did it heal bones properly?
Knowledge-focused CompletedThe study is a monocentric, retrospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to confirm safety, performance and clinical benefits of the Reconstruction System (implants and instrumentation) when used for temporar…
Sponsor: Zimmer Biomet • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Chill training: could 8 days of cold boost your grip?
Knowledge-focused CompletedIn cold weather environments, blood flow to the extremities is significantly reduced, which severely impairs hand function and induces thermal discomfort. Prolonged or repeated cold exposure elicits an adaptive habituation response that is characterized by blunted skin vasoconstr…
Phase: NA • Sponsor: United States Army Research Institute of Environmental Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Baby belly rubs tested as jaundice prevention
Prevention OngoingThe proposed study will incorporate an intervention previously un-studied in the US healthcare setting for prevention of hyperbilirubinemia
Phase: NA • Sponsor: University of California, Davis • Aim: Prevention
Last updated Jun 26, 2026 19:01 UTC
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Scientists probe gene signals in colorectal tumors
Knowledge-focused CompletedCollect some tumor tissue specimens from patients who have undergone colorectal cancer surgery and conduct experiments such as immunohistochemistry to observe the expression of related genes in colorectal cancer.
Sponsor: hui hou • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Nurse practitioners get ultrasound training boost in new study
Knowledge-focused OngoingThis project aims to establish point-of-care ultrasound (PoCUS) training course for nurse practitioners in Taiwan, and standardized evaluation modules. The study subjects are nurse practitioners across different hospital levels. I
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Massive cancer registry aims to improve Real-World treatment insights
Knowledge-focused Recruiting nowThis is an observational registry for patients at participating oncology centers. The data collection includes but is not limited to baseline variables, treatments given and outcome data. Patient surveys are also included. The aim of the study is to generate rich and standardized…
Sponsor: N-Power Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Study examines blood thinner use in heart patients prone to stomach bleeds
Knowledge-focused CompletedThis study is a retrospective analysis of observational cohorts using data from prospectively collected administrative/claims data to investigate treatment patterns, and safety and effectiveness outcomes in patients with NVAF with high risk of gastrointestinal bleed who initiate …
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Pharmacist alerts may beat doctor alerts for blood thinner safety
Knowledge-focused CompletedThe researchers hypothesize that existing-prescription notifications directed to pharmacists are more likely to lead to a prescription change than existing-prescription notifications directed to prescribers. Furthermore, the researchers hypothesize that the availability of a phar…
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Parkinson's apathy drug trial stalls after just 8 patients
Symptom relief TerminatedApathy is defined as a lack of feeling, emotion, interest, or concern. Apathy also involves reduction or loss of motivation and goal-directed behavior. Clinically significant apathy, where meaningful activities are given up and quality of life is diminished, is common in people w…
Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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New brain drug ITI-333 tested in healthy volunteers for first time
Knowledge-focused CompletedThis is an open-label, single-dose study of up to 4 dose levels of ITI-333 in healthy male and female subjects. Each cohort will enroll 6 subjects. Subjects will have a baseline PET/CT scan and a postdose PET/CT scan using \[14C\]-MDL100907 to characterize 5-HT2A receptor occupan…
Phase: PHASE1 • Sponsor: Intra-Cellular Therapies, Inc. • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:21 UTC
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Can chatting about End-of-Life care in groups make a difference?
Knowledge-focused OngoingThe main goal of the ENACT (ENgaging in Advance Care planning Talks) Group Visit intervention is to integrate a patient-centered advance care planning process into primary care, ultimately helping patients to receive medical care that is aligned with their values. The ENACT Group…
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC