Kids' painkiller mystery: anesthesia may change how oxycodone works
NCT ID NCT03054831
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how general anesthesia changes the way children process liquid oxycodone, a common painkiller used after surgery. Researchers will give the drug to 40 children aged 2-8 at different times during anesthesia and measure its levels in the blood. They will also check if certain genes affect how the drug is broken down. The goal is to understand how to dose oxycodone more safely in kids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- liquid oxycodone
- What this could lead to
- If successful, this could help doctors give safer, more effective pain relief to children during and after surgery.
- What could go wrong
- This is a small, early-phase study with only 40 children. It focuses on drug levels, not on proving pain relief or safety. Results may not apply to all kids.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Boston Children Hospital
Boston, Massachusetts, 02115, United States