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127005 trials found · Page 5244 of 6351
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Which dry eye drop works faster? new study pits diquafosol against rebamipide
Symptom relief CompletedThis study compares the immediate therapeutic and mucin-secreting effects 30 minutes after instillation of 3% diquafosol and 2% rebamipide in dry eye disease.
Phase 4 • Sponsor: Korea University Anam Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New program aims to boost PrEP use among latino men at risk for HIV
Prevention CompletedThe clinical study will evaluate the feasibility and acceptability of a culturally tailored behavioral intervention to improve uptake of pre-exposure prophylaxis for HIV prevention among at-risk Latino men who have sex with men.
Sponsor: University of California, Los Angeles • Aim: Prevention
Last updated Jun 27, 2026 12:10 UTC
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Small study probes bleeding danger in stroke patients with 'leaky' brain vessels
Knowledge-focused CompletedBackground: In stroke patients treated with intravenous thrombolysis (IVT), presence and high number of strictly lobar cerebral microbleeds (compatible with cerebral amyloid angiopathy, CAA) seems to be associated with increased risk of hemorrhagic transformation, symptomatic hem…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Could controlled Low-Oxygen breathing prevent dangerous blood pressure swings in spinal injury?
Disease control Recruiting nowThe prevalence of autonomic dysfunction and sleep disordered breathing (SDB) is increased in individuals with spinal cord injury (SCI). The loss of autonomic control results in autonomic dysreflexia (AD) and orthostatic hypotension (OH) which explains the increase in cardiovascul…
Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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New online tool aims to stop teen dating violence before it starts
Prevention CompletedThe purpose of this study is to develop and evaluate a multi-level (youth, parent, school) Internet-based dating violence prevention program, 'Me \& You-Tech' (MYT) for 6th-grade middle school students.
Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Jun 27, 2026 08:06 UTC
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Dental implant showdown: old guide vs. High-Tech screen
Knowledge-focused Recruiting nowImplant placement is preplanned by taking xrays and impressions for the mouth one group a guide is fabricated and used to guide the implant drilling all through to the implant placement the other group, no guide is fabricated, but the implant is placed by dynamic navigation throu…
Phase 4 • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Head-to-Head: which pill tames high blood pressure better in younger adults?
Disease control CompletedRandomized comparison of bisoprolol 2.5 mg monotherapy with fix combination drug valsartan 80 mg- amlodipine 5 mg
Phase 4 • Sponsor: Shiraz University of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New tool helps patients and therapists make better choices for leg pain
Knowledge-focused CompletedIntermittent claudication is the most common symptom of peripheral arterial disease (PAD). The recommended therapy is supervised exercise therapy combined with lifestyle counselling, provided by a physiotherapist. Ideally, during the treatment process patients' values and prefere…
Sponsor: Radboud University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Could chewable tablets replace the nasty glucose drink for pregnancy diabetes testing?
Diagnosis CompletedThe purpose of this study is to compare the positive and negative effects of Dex4® tablets, as an alternative form of fast acting carbohydrate, compared to the current standard diagnostic test, glucose beverage. The investigators hypothesis that because of their availability in s…
Phase 2 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
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Probiotic pill may beat dancer fatigue, small study hints
Symptom relief CompletedThe aim of the planned research is to assess the dynamics of changes in the elements of the gut-brain axis (GBA), the cytokine profile and the endocannabinoid system markers, after dietary supplementation with probiotics Lactobacillus helveticus Rosell-52 and Bifidobacterium long…
Sponsor: Poznan University of Physical Education • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New study tracks antifungal drug in sick kids
Knowledge-focused Recruiting nowCaspofungin is an anti-fungal drug mainly metabolized by the liver. The pathophysiological status of children with severe infection will affect the metabolism of caspofungin in the body especially in the case of liver dysfunction. There is little metabolism of caspofungin through…
Sponsor: Children's Hospital of Fudan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New air bubble technique may help treat thin corneas in keratoconus
Disease control Completedin this study we evaluated the effectiveness and safety of corneal collagen cross-linking in keratoconic eyes with thin cornea after induction of stromal emphysema prior to riboflavin instillation and UV-A corneal irradiation
Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Personalized parenting: study aims to match therapy to each Child's needs
Knowledge-focused Recruiting nowThis study will develop and test whether personalized profiles of children with Disruptive Behaviour Disorder (DBD) and their parents based on important psychological, emotional, and neuropsychological indicators predict their response to child cognitive behavioral treatment and …
Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Could simple blood tests spot sepsis sooner?
Knowledge-focused CompletedThe aim of this study is to investigate, in patients admitted to the intensive care unit either for reasons other than sepsis who subsequently develop sepsis or with a primary diagnosis of sepsis, whether monocyte distribution, monocyte-to-lymphocyte ratio, and neutrophil-to-lymp…
Sponsor: Oguz Gundogdu • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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New eye exam gadgets could replace dilation drops for kids
Diagnosis CompletedThis study aimed to compare refractive measurements using Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic refraction serving as the gold-standard. This a ret…
Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Jun 27, 2026 12:36 UTC
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Voice swap: simple recording may boost NICU bonding and breastfeeding
Symptom relief CompletedThis randomized controlled trial evaluates the effect of reciprocal maternal-infant voice exposure on maternal attachment and breastfeeding outcomes in a neonatal intensive care unit (NICU). Infants in the intervention group are exposed to recordings of their mothers' voices, whi…
Sponsor: Biruni University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Personalized exercise program shows promise for neck dystonia relief
Symptom relief Recruiting nowDystonia is involuntary movements characterized by posture abnormalities or repetitive movements as a result of continuous or intermittent simultaneous contraction of opposing muscle groups. Dystonic movements are twisted and twisted in a certain pattern. Dystonia is named in dif…
Sponsor: Prof. Dr. Şehim Kutlay • Aim: Symptom relief
Last updated Jun 26, 2026 17:55 UTC
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Could tiny needles tame Chemo's Gut-Wrenching side effect in kids?
Symptom relief CompletedTo evaluate the feasibility of an acupuncture protocol in the prevention of late diarrhea due to irinotecan in pediatric patients with solid tumors, a pre-post pilot study will be conducted. Pre-post pilot study non-randomized, open label, single arm study. There will be a singl…
Sponsor: Fundació Sant Joan de Déu • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Your phone may help tame diabetes and obesity
Disease control Recruiting nowThe purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and type II diabetes outcomes in type 2 diabetics. This study will involve a 6-month long commitment where participants will be expected to weigh themselves ever…
Sponsor: San Diego State University • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New study reveals how cancer treatment affects swelling and quality of life
Knowledge-focused CompletedLymphedema in the head and neck area is common after treatment for head and neck cancer. The aim of the research project is: • to assess the prevalence of lymphedema in patients with head and neck cancer (HNC) by measuring the amount of tissue water in the head and neck area be…
Sponsor: Lund University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC