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127005 trials found · Page 5242 of 6351
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Can an online program help teen moms prevent repeat pregnancies?
Prevention OngoingThe purpose of the study is to determine the impact of the offer to participate in the Young United Parents! (YUP!) intervention relative to the control condition on use of effective non-barrier contraception and frequency of vaginal sex without condoms three months after the int…
Sponsor: The Policy & Research Group • Aim: Prevention
Last updated Jun 27, 2026 12:24 UTC
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Ventilator Patients' diaphragm decline measured in new study
Knowledge-focused Recruiting nowThe gold standard of twitch transdiaphragmatic pressure recordings would ultimately clear the fog around the rate of development of Ventilator induced Diaphragm Dysfunction (VIDD) in mechanically ventilated patients over time. Through measurements made even after mechanical vent…
Sponsor: RWTH Aachen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Could a fruit compound ease carpal tunnel pain?
Symptom relief CompletedThis research study is being conducted to investigate the safety and effectiveness of the drug Fisetin for mild or moderate carpal tunnel syndrome (CTS).
Phase 2 • Sponsor: Peter C. Amadio, M.D. • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Heart-Lung machine showdown: which oxygenator spares your platelets?
Knowledge-focused CompletedOpen-heart surgery requires temporarily stopping the heart and lungs and diverting the patient's blood to an outside system that takes over the function of the heart and lungs. This is possible through the use of cardiopulmonary bypass (CPB) which diverts blood, through plastic t…
Sponsor: BRADEN DULONG • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Prepackaged Heart-Healthy meals tested in small pilot study
Prevention CompletedThe proposed project explores the acceptability and health benefits of ready-to-eat (RTE) meals based on the Dietary Approaches to Stop Hypertension (DASH) eating plan. The researchers have developed 14 recipes following the DASH eating plan, which is recommended for the preventi…
Sponsor: Washington State University • Aim: Prevention
Last updated Jun 27, 2026 13:02 UTC
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Baby formula boost: can a nutrient blend make infants smarter?
Knowledge-focused CompletedThe purpose of this study is to demonstrate the efficacy of the nutrient blend in a starter infant formula (IF) and follow up infant formula (FUF) in improving the neurocognitive and behavioural outcomes among formula-fed infants randomized to the experimental formula (EF) versus…
Sponsor: Société des Produits Nestlé (SPN) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Game-Based badminton teaching may boost tactical skills over drills
Knowledge-focused CompletedEvaluating the Effectiveness of the Tactical Game Model in Teaching Badminton: A Quasi-Experimental Study This study investigated the effectiveness of the Tactical Game Model (TGM) in teaching badminton, aiming to determine its impact on students' tactical awareness, decision-ma…
Sponsor: Zonguldak Bulent Ecevit University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Can a phone app help you sleep better when you have chronic pain?
Symptom relief CompletedThe aim of this randomized clinical trial is to evaluate the effectiveness of app-delivered cognitive-behavioral therapy for insomnia adjunct to inpatient multimodal rehabilitation for individuals with comorbid insomnia and chronic pain, compared with rehabilitation (usual care) …
Sponsor: Norwegian University of Science and Technology • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC
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New tablet game helps stroke survivors regain arm control
Symptom relief CompletedHemiparesis is a frequently observed symptom of stroke. There are various therapy options that are used in the rehabilitation of patients. Some studies have shown that, in addition to unilateral arm training, bilateral arm training can also lead to positive results in treatment a…
Sponsor: BDH-Klinik Hessisch Oldendorf • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Smartwatch study aims to get people moving more
Symptom relief CompletedThe purpose of this study is to determine the efficacy of a new digital health tool that uses a phone and smartwatch to encourage physical activity and increase weekly amounts of Moderate to Vigorous Physical Activity (MVPA) over 12 months among adults compared to a digital healt…
Sponsor: University of California, San Diego • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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New home therapy boosts seniors' independence
Symptom relief CompletedThe objective of this project is to pilot test an ADL (activities of daily living)-enhanced program as an adjuvant therapy to usual home health rehabilitation to improve patient outcomes. The project will compare the ADL-enhanced program plus usual care with usual care using an R…
Sponsor: University of Florida • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Gum disease showdown: which antibiotic gel works best for diabetics?
Disease control CompletedThis clinical study randomized 380 diabetic chronic periodontitis patients into 4 groups: scaling and root planning alone (group I), scaling and root planning plus metronidazole gel (group II), scaling and root planning plus minocycline gel (group III), and scaling and root plann…
Sponsor: Riphah International University • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New PET tracer aims to reveal hidden inflammation in cancer patients
Diagnosis Recruiting now18F-4FN represents a novel PET agent for imaging inflammation. Acute inflammatory signaling through the TLR axis recruits neutrophils and macrophages to inflammatory sites. Both cells activate the production of high energy reactive oxygen species/reactive nitrogen species (RONS),…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Aug 22, 2026 00:00 UTC
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Simpler surgery for pelvic organ prolapse may be just as effective
Disease control CompletedThis is a prospective, randomized, multicenter, non-inferiority trial including women with stage II-IV apical pelvic organ prolapse (POP), classified according to the POP-Q system. Participants will be randomized into two groups: Group A: laparoscopic colposacropexy with posteri…
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New study tests better ways to fix receding gums
Disease control Completed24 patients will be treated with a coronally positioned tunnel with AlloDerm RTM with or without the addition of Enamel Matrix Derivative to compare the baseline and 6-month changes in recession defect coverage, clinical attachment levels, amount of keratinized tissue width, and …
Phase 4 • Sponsor: University of Louisville • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Which putty preserves your jawbone best? new trial tests two graft materials
Disease control CompletedThe primary aims of this study are to compare, after 4 months, the clinical and histologic results of a combination demineralized/mineralized putty allograft vs. synthetic calcium phosphosilicate (CPS) putty alloplast graft utilization in socket preservation procedures. A regener…
Phase 4 • Sponsor: University of Louisville • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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10-Year study tracks safety of silimed smooth breast implants
Disease control Recruiting nowThe study investigates the safety and performance of Silimed® brand smooth surface breast implants in women born with indication for primary and secondary (revision) augmentation to be followed up for 10 years. The safety of the smooth-surfaced Silimed® implant will be evaluated …
Sponsor: Silimed Industria de Implantes Ltda • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Double nerve block may ease pain after chest surgery
Symptom relief By invitation onlyThis research is being done to evaluate the effects of receiving only a paravertebral block prior to first rib resection procedure versus receiving the block both pre and post procedure.
Phase 4 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Experimental lung cancer drug MGY825 tested in early trial
Disease control Stopped earlyStudy of MGY825 single agent in adult patients with advanced non-small cell lung cancer.
Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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New imaging test aims to predict chemotherapy outcomes in rare brain cancer
Diagnosis Stopped earlyThis will be an open, single-arm, international, multicentre, phase II imaging study to assess the predictive value of \[68Ga\]Ga PentixaFor PET imaging in primary and isolated secondary central nervous system lymphoma (CNSL) patients scheduled to undergo induction chemotherapy.
Phase 2 • Sponsor: Pentixapharm AG • Aim: Diagnosis
Last updated Jun 26, 2026 13:53 UTC