New imaging test aims to predict chemotherapy outcomes in rare brain cancer

NCT ID NCT05222269

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a special PET scan using a tracer called 68Ga-PentixaFor could predict how well patients with central nervous system lymphoma respond to chemotherapy. The plan was to scan patients before, during, and after treatment and see if the scan results matched their long-term outcomes. However, the trial was stopped early after enrolling only one person, so we do not have enough information to know if this approach works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

68Ga-PentixaFor (a radioactive tracer for PET imaging)

What this could lead to

If successful, this imaging method could help doctors predict which patients will respond to chemotherapy, potentially guiding more personalized treatment.

What could go wrong

The trial was terminated after enrolling only 1 participant, so no meaningful conclusions can be drawn. It is unclear if the approach works or is practical.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

primary central nervous system lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Aalborg

    Aalborg, 9000, Denmark

  • University Hospital CHU Nantes

    Nantes, 44093, France