CNS LYMPHOMA
Clinical trials for CNS LYMPHOMA explained in plain language.
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Radioactive hope: new drug targets Hard-to-Treat brain lymphoma
Disease control Recruiting nowThis early-phase trial tests a radioactive drug called [90Y]Y-PentixaTher in 15 people with recurrent or refractory central nervous system (CNS) lymphoma. The drug is given once through a vein, and researchers will check safety, where the drug goes in the body, and whether it shr…
Matched conditions: CNS LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Pentixapharm AG • Aim: Disease control
Last updated May 17, 2026 00:46 UTC
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New drug cocktail targets brain lymphoma in early trial
Disease control Recruiting nowThis early-phase study tests a combination of drugs (zanubrutinib, Pola-R-CHP, and high-dose methotrexate) in 20 adults with large B-cell lymphoma that has spread to the brain or spinal cord. The main goal is to check for side effects and find safe doses. Researchers will also tr…
Matched conditions: CNS LYMPHOMA
Phase: PHASE1 • Sponsor: Juan P. Alderuccio, MD • Aim: Disease control
Last updated May 17, 2026 00:45 UTC
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Dual-Target CAR t cells offer new hope for tough lymphoma
Disease control Recruiting nowThis early-phase trial tests a new type of immunotherapy called CD19x22 CAR T cells in people aged 16 and older with B-cell non-Hodgkin lymphoma that has come back or not responded to treatment. The therapy uses the patient's own immune cells, modified to attack two targets on ca…
Matched conditions: CNS LYMPHOMA
Phase: PHASE1 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 15, 2026 11:54 UTC