CNS LYMPHOMA
Clinical trials for CNS LYMPHOMA explained in plain language.
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New antibody combo aims to treat brain lymphoma
Disease control Recruiting nowThis trial investigates a combination of two drugs—tafasitamab, an antibody given by IV, and lenalidomide, an oral medication—for people with relapsed central nervous system (CNS) lymphoma. The study includes up to 35 participants and is the first to test this antibody in CNS lym…
Matched conditions: CNS LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: James Rubenstein • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Dual-Target CAR t cells take on tough lymphoma
Disease control Recruiting nowThis early-phase study tests a new type of immunotherapy called CD19x22 CAR T cells for teenagers and adults with B-cell non-Hodgkin lymphoma that has come back or not responded to treatment. The therapy uses a patient's own immune cells, modified to attack two targets on cancer …
Matched conditions: CNS LYMPHOMA
Phase: PHASE1 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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New hope for Hard-to-Treat brain cancer: targeted radiation trial launches
Disease control Recruiting nowThis early-phase study tests a new drug called [90Y]Y-PentixaTher for people with central nervous system (CNS) lymphoma that has come back or not responded to standard treatments. The drug delivers radiation directly to cancer cells. About 15 participants will receive one intrave…
Matched conditions: CNS LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Pentixapharm AG • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New cocktail targets brain lymphoma: early trial launches
Disease control Recruiting nowThis early-stage trial tests whether adding the targeted drug zanubrutinib to a standard chemotherapy regimen (Pola-R-CHP plus high-dose methotrexate) is safe for people with large B-cell lymphoma that has spread to the central nervous system (brain or spinal cord). About 20 adul…
Matched conditions: CNS LYMPHOMA
Phase: PHASE1 • Sponsor: Juan P. Alderuccio, MD • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC