New drug cocktail targets brain lymphoma in early trial

NCT ID NCT06730542

First seen May 15, 2026 · Last updated May 15, 2026

Summary

This early-phase study tests a combination of drugs (zanubrutinib, Pola-R-CHP, and high-dose methotrexate) in 20 adults with large B-cell lymphoma that has spread to the brain or spinal cord. The main goal is to check for side effects and find safe doses. Researchers will also track how well the tumors shrink. This is not a cure; it aims to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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