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127005 trials found · Page 5238 of 6351
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New nerve block may ease knee surgery pain without slowing you down
Symptom relief CompletedSelective blockade of the saphenous nerve branches is among the regional anesthesia techniques in knee surgery. In this block, analgesia is provided without motor block and is an essential advantage in terms of early mobilization in the postoperative period. Blockage of motor bra…
Sponsor: Medipol University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Could probiotics calm rosacea? new trial tests daily capsules
Disease control CompletedThe clinical trial has a randomized, double-blind, placebo-controlled design, in which the aim is to evaluate the effect of a probiotic mix, with a 12-week treatment, on the evolution of rosacea. This 12 weeks of treatment are structured into three visits: Visit 1 (initial; week…
Sponsor: Bionou Research, S.L. • Aim: Disease control
Last updated Jun 26, 2026 19:18 UTC
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Brain zaps tested for mysterious dementia
Knowledge-focused CompletedThis is a pilot study to identify a homogeneous cohort of pathologically specific dementia with SNAP for clinical trial of brain stimulation.
Sponsor: Chang Gung Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Playtime before surgery: bubbles and stories may ease anxiety in kids and parents
Symptom relief CompletedIt is emphasized in studies that child and parent anxiety that arises in pediatric surgery should be prevented or reduced. According to previous studies, one way to reduce child and parent anxiety in the preoperative period is therapeutic play interventions. This study was planne…
Sponsor: Isparta University of Applied Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Heart surgery pain relief: which method works best?
Symptom relief CompletedThe purpose of this prospective randomized controlled trial is to compare the effectiveness of two different delivery methods for postoperative pain management following cardiac surgery requiring median sternotomy: intermittent programmed LA bolus versus continuous LA infusion th…
Phase 4 • Sponsor: Henry Ford Health System • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Quick test could spare kids from strong antibiotics for UTIs
Disease control Stopped earlyINVICTUS PED primary objective is to show the non-inferiority of an empirical antibiotic therapeutic management guided by the early detection of integrons in the urine, compared to a usual empirical antibiotic treatment, for the recovery of children admitted to the pediatric emer…
Sponsor: University Hospital, Limoges • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Can olive oil and nuts tame psoriasis? new study tests diet plus biologics
Disease control Recruiting nowIn this study, participants will have 3 or 4 total study visits over approximately 10 total weeks. There is a two week medication washout period in between the 1st and 2nd visits. This washout only applies if participants are using a prohibited psoriasis medication (such as topic…
Sponsor: University Hospitals Cleveland Medical Center • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Heart scan may forecast ICU stay for babies with severe bronchiolitis
Knowledge-focused CompletedIn this prospective study, we aim to evaluate the association between an echocardiographic marker of right ventricular systolic function, the TAPSE (Tricuspid Annular Plane Systolic Excursion), and poor outcome in patients admitted to Pediatric Intensive Care Unit (PICU) for Acut…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Marathon runners may face higher colon cancer risk, study suggests
Knowledge-focused CompletedThe purpose of this study is to determine the frequency of colorectal cancer in male and female endurance athletes between the ages of 35 and 50.
Sponsor: Inova Health Care Services • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Smart reports guide doctors to better antibiotic choices
Knowledge-focused CompletedThe main goal of this study is to use automated electronic reports to assess and improve guideline-concordant antibiotic use for: 1\) adult inpatients with community-acquired pneumonia; 2) pediatric inpatients with community-acquired pneumonia; 3) adult outpatients with acute ph…
Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New program aims to boost living kidney transplants in alberta
Knowledge-focused OngoingFor people living with kidney failure, the two active treatment options are dialysis or kidney transplantation. Transplantation is optimal, and especially from a living donor - offering patients longer survival, a better quality of life, and cost savings for the health system whe…
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Rooming with a pro: new study tests peer support for breastfeeding confidence
Knowledge-focused CompletedThe World Health Organization (WHO) states that peer support breastfeeding education programs are effective interventions for improving breastfeeding outcomes. In this context, the WHO's Global Strategy for Infant and Young Child Feeding recommends the implementation of "lay heal…
Sponsor: Ege University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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AI-Powered smiles: could smart monitoring shorten braces time?
Disease control Recruiting nowThe decision on aligner changing is based on orthodontists' personal experience and common knowledge that an approximated time span for the aligner have exhausted its biological efficacy. However, a one size fits all approach is not always ideal, as an average determined time is …
Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Tiny study probes why shoulders get stiff after birth nerve damage
Knowledge-focused CompletedThe purpose of this prospective work is to study the consequences of obstetrical brachial plexus paralysis on the rotator muscles of the shoulder. The hypothesis is that shoulder stiffness of these children is due to an impairment of the shoulder rotator muscles. The investigator…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Does washing fat before facial grafting give better skin results?
Symptom relief CompletedThe goal of this study is to specifically examine changes in facial skin appearance after facial fat grafting with autologous fat tissue that has either been washed with sterile saline before injecting, or left unwashed. This will be testing two variations of a standard of care s…
Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Massive study aims to unlock secrets of movement disorders
Knowledge-focused Recruiting nowBackground: A movement disorder is a condition that causes a person s body to move in ways that are not normal. There are different types. Some disorders cause movements people can t control, such as tics or shaking. Some cause reduced or slow movements. Movement disorders can c…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Ecuador study monitors therapy outcomes to boost mental health care
Knowledge-focused OngoingThis is a naturalistic study implementing a routine outcome monitoring system to track clients' change and outcomes at the Centro de Psicología Aplicada (CPA) of the Universidad de Las Américas in Quito, Ecuador
Sponsor: Universidad de las Americas - Quito • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Experimental Lymph-Node injection for skin cancer trial halted early
Disease control Stopped earlyThis phase Ib trial tests the safety, side effects, and best dose of STI-3031 given directly into the into the lymph nodes or the lymph vessels (intra-lymphatic) using the Sofusa DoseConnect device in treating patients with melanoma that has spread through a lymph vessel and begi…
Phase 1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Reusable surgical clips prove safe and effective in 245-Patient study
Disease control CompletedThis is a Post-Market Clinical Follow-up (PMCF) investigation to determine the long-term effectiveness and safety of the Multi-Fire Clip System in laparoscopic surgery. This system consists of two medical devices, the M/L-10 Clip Applier and the M/L-10 Clip. The Multi-Fire Clip S…
Sponsor: Microline Surgical, Inc. • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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New study tests if software can spot dye in liver tumors during radiation
Knowledge-focused Recruiting nowThis observational study will investigate the properties of image files standardly collected during radiation therapy treatment in a cross-section of liver cancer patients who received stereotactic ablative body radiation therapy (SABR) after trans-catheter arterial chemo emobili…
Sponsor: University of Sydney • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC