Tiny study probes why shoulders get stiff after birth nerve damage
NCT ID NCT05403034
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study examined muscle cells from 8 children with obstetrical brachial plexus palsy, a birth injury that affects arm nerves. Researchers took small muscle samples during planned shoulder surgery to see if the cells can repair themselves. The goal was to understand why shoulders become stiff and to build a model for testing future treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward new therapies to improve shoulder muscle function in children with brachial plexus palsy.
- What could go wrong
- This is a very small, early-stage study (8 participants) focused on understanding basic biology, not testing a treatment. Results may not lead directly to new therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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8 people
The number who actually took part.
- Started
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Oct 2022
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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2 to 15 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * OBPP children with a planned shoulder surgery (arthrolysis and/or muscle transfer). Exclusion Criteria: * other neurological disorders, post-traumatic shoulder stiffness
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chu Montpellier
Montpellier, 34000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.