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116076 trials found · Page 5153 of 5804
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Can mindful eating tame Post-Surgery binges?
Symptom relief CompletedThe goal of this clinical trial was to see if learning and practicing mindful eating in a group was helpful for people who had bariatric surgery. The main questions it aims to answer are: 1. Does learning and practicing mindful eating help decrease overeating, improve mood, decr…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jun 26, 2026 13:04 UTC
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Scientists hunt for hidden triggers of deadly newborn infection
Knowledge-focused CompletedStreptococcus agalactiae (GBS) is the leading cause of neonatal septicaemia, meningitis, and pneumonia in the industrialized world. Early onset (EOD) and late onset (LOD) diseases are defined in neonates by their occurring within or after the first week of life, respectively. Mol…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:27 UTC
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New elbow implant under study for severe joint damage
Disease control Recruiting nowThe objectives of the study are to confirm safety and performance of the Zimmer Nexel Total Elbow when used in primary or revision total elbow replacement.
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Can better knee measurements lead to happier patients after surgery?
Knowledge-focused CompletedThe knee prosthesis is a validated treatment for end-stage osteoarthritis, and this intervention usually provides a significant improvement in the quality of life of patients. However, a significant percentage of patients (up 30%) say disappointed with the outcome of the interven…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:25 UTC
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Can a video game help Parkinson's patients walk steadier?
Knowledge-focused CompletedIn this study the investigators aim to assess the feasibility and acceptability of a serious game to rehabilitate gait and balance disorders in 10 patients with Parkinson's disease previously operated for deep brain stimulation of the sub thalamic nucleus.
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Back pain relief might come from a piggy bank – no coins needed
Symptom relief CompletedInvestigators will conduct a randomized controlled trial of a 30-day positive activities intervention, Positive Piggy Bank, compared to a Wait-List control group (Figure 2). Prior to their scheduled appointment to undergo epidural steroid injection, all patients meeting study cri…
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Radiation's hidden toll: new study tracks late effects in NPC survivors
Knowledge-focused OngoingNasopharyngeal carcinoma (NPC) is a type of head and neck cancer. The last three decades of research in head and neck radiation oncology have largely focused on improvements in survival, which have mostly come at the cost of long term toxicity for surviving patients. This is an …
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Robot arm trainer shows promise for kids with nerve conditions
Knowledge-focused CompletedThe purpose of this study is to investigate the applicability and feasibility of the newly developed robot platform for upper extremity therapy ("ChARMin") in children undergoing neurorehabilitation.
Phase: NA • Sponsor: Huub van Hedel • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Eye surgery showdown: which technique spares more corneal cells?
Knowledge-focused CompletedCataract is the clouding of the lens of the eye, which initially prevents clear vision and eventually progresses to blindness if left untreated. Cataract remains the leading cause of blindness and an important cause of visual impairment across the globe. Cataract surgery by ultra…
Phase: NA • Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Gut bacteria may worsen liver disease – new study investigates
Knowledge-focused CompletedBackground: \- Hepatitis C infection (HCV) is a leading cause of liver disease. Normal bacteria from the intestines may spread to the liver and blood during liver disease. This is called bacterial translocation (BT). Researchers think BT may cause liver disease to worsen. Objec…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Gene hunt: which drug combo works best for colorectal cancer?
Knowledge-focused OngoingThe purpose of this study is to investigate biomarkers which may be predictors of efficacy and safety of treatment with mFOLFOX6 + bevacizumab versus mFOLFOX6 + panitumumab therapy in patients with chemotherapy-naïve unresectable advanced or recurrent colorectal cancer.
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can we predict type 1 diabetes before it starts?
Knowledge-focused CompletedThe purpose of this study is to determine whether early immunological markers (activation of autoreactive T lymphocytes) precede and are predictive of the appearance of autoantibodies in children born from type 1 diabetic parents.
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Weight may influence breast cancer drug response, study suggests
Knowledge-focused TerminatedMore than three quarter of patients with breast cancer are treated by hormone pills called tamoxifen and aromatase inhibitors (AIs). AIs are drugs that stop female hormone production. This hormone production mostly happens in fat, muscle, and breast tissue in postmenopausal women…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Can a fentanyl spray stop pain during cancer radiation?
Symptom relief CompletedThe clinical trial is a stage 3 study to determine the role of fentanyl transmucosal in the prevention of pain induced by mobilization in patients receiving a bone metastasis radiation for bone metastasis irradiations
Phase: PHASE3 • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Could a common blood pressure drug shrink kidney tumors?
Disease control TerminatedTreatment of angiomyolipomas is based on invasive techniques such as surgery or embolization. Development of anti-angiogenic therapies is a major and growing field of research in hypervascularized tumors. Angiomyolipomas have been shown to regress after prolonged treatment with m…
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Cancer Patients' samples fuel future drug discovery
Knowledge-focused Recruiting nowThis study collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer…
Sponsor: National Cancer Institute LAO • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Autism vs bipolar: scientists compare emotional reactions
Knowledge-focused CompletedThe objective of this study is to identify the specific characteristics of Autism Spectrum Disorder (ASD) in emotional response profiles and shared with Bipolar Disorder (BD) characteristics.
Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists watch brain diseases unfold to find better ways to diagnose and treat
Knowledge-focused Recruiting nowBackground: \- Inflammation is how the body reacts to infection or injury. Infections or inflammation in the brain and nerves can be serious. There aren t always good tests to detect this. Researchers want to learn more about how diseases affect the brain and nerves to develop b…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Can a simple diet and exercise program cut obesity in the mexican community?
Disease control ENROLLING_BY_INVITATIONThe Mexican Consulate runs a Ventanilla de Salud (VDS) (Health Window) program in fifty locations nationwide. The VDS provides an opportunity to provide health services to members of the Mexican community. Some of the concerns previously identified during the work at the VDS were…
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Could a Fiber-Rich formula help control diabetes in Tube-Fed patients?
Disease control CompletedThis study aims to evaluate the effects of a fiber-enriched, sodium-controlled enteral nutrition formula on glycemia, blood pressure, and nutritional status in long-term care residents with diabetes receiving tube feeding. Participants receive the enteral formula as their sole so…
Phase: NA • Sponsor: Taipei Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC