Massive study tracks 1,100+ kids after cancer treatment to uncover hidden risks

NCT ID NCT05564026

Recruiting now Knowledge-focused Sponsor: Children's Oncology Group Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows over 1,100 children who were treated for germ cell tumors (a type of cancer). Researchers want to learn about long-term side effects like hearing loss and to analyze tumor DNA to better predict which children might have their cancer come back. Participants provide health questionnaires and blood or saliva samples, but no new treatments are being tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better predict which children are at risk for treatment side effects or relapse, leading to more personalized care.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly help participants. Results may take years and might not change current practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

childhood germ cell tumor choriocarcinoma embryonal carcinoma Endodermal Sinus Tumor germ cell tumor germinoma mixed germ cell tumor Neoplasms, Germ Cell and Embryonal teratoma yolk sac tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHORIOCARCINOMA EMBRYONAL CARCINOMA GERM CELL TUMOR GERMINOMA LATE EFFECTS MIXED GERM CELL TUMOR PEDIATRIC GERM CELL TUMOR TERATOMA YOLK SAC TUMOR

Contacts and locations

Locations

University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States

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