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116076 trials found · Page 5140 of 5804
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Which nerve block is best for knee surgery recovery?
Symptom relief CompletedThe purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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New monitoring method may help doctors manage blood pressure during heart surgery
Knowledge-focused CompletedCentral and peripheral arterial pressure decoupling occurs in some clinical conditions like sepsis or cardiopulmonary bypass. This decoupling may leed to unsuitable decisions such as the use of catecholamines. The aim of this study is to evaluate the pulse wave's speed as a mark…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:01 UTC
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Sniffing out clues: smell tests may reveal brain secrets in bipolar disorder
Knowledge-focused CompletedTo compare olfactory performance between patients with BD and HC and correlate their performances to neuroimaging data
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:36 UTC
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Researchers track rare artery disease affecting the lungs
Knowledge-focused Recruiting nowThe purpose of this study is to identify the clinical features, management pattern and long-term outcomes of patients with pulmonary arteries involvement in Takayasu's arteritis (TAK-PAI).
Sponsor: China-Japan Friendship Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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30,000 HIV patients enrolled in massive french observational study
Knowledge-focused Recruiting nowThe objective of the Dataids cohort is to continue a long-term, prospective collection of clinical, laboratory and therapeutic data on a large cohort of HIV infected patients seeking care in 15 HIV centers in France in order : 1. to provide and develop a surveillance system to d…
Sponsor: DatAids • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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700 liver transplant patients studied to uncover hidden clot risks
Knowledge-focused Recruiting nowThe goal of this observational study is to investigate the correlation between portal vein thrombosis (PVT) and the prognosis of liver transplantation. The main questions it aims to address are: What is the prevalence of PVT? What are the risk factors associated with PVT? What i…
Sponsor: Ru-zhou Cai • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:51 UTC
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Blood protein may hold key to unexplained miscarriages and IVF failures
Knowledge-focused Recruiting nowA low plasma level of mannose binding lectin (p-MBL) is associated with unexplained recurrent pregnancy loss (RPL), but it is not investigated if it is associated with unexplained reproductive failure in general, including recurrent implantation failure (RIF) after assisted repro…
Sponsor: Aalborg University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Smartwatches and video calls could ease cancer care for rural patients
Symptom relief CompletedObservational study about patients treated for a metastasis breast cancer who live far from their comprehensive cancer center and followed by telemedicine, connected watches and patient-reported symptom monitoring.
Sponsor: Institut Bergonié • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Mineral baths may affect heart health in osteoarthritis patients
Knowledge-focused CompletedThis prospective observational study aims to evaluate changes in heart function using echocardiography before and after a standardized balneotherapy program in adult and elderly patients with osteoarthritis. Balneotherapy is commonly used by patients with osteoarthritis, especia…
Sponsor: Bursa City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Heart wire removal procedure analyzed in 702 patients
Knowledge-focused CompletedThe number of devices for cardiac pacing and defibrillation has increased in recent years. However, although they have improved in terms of quality and extended lifespan after implantation, they are not free from complications. The Achilles' heel of cardiac implantable electronic…
Sponsor: Medical University of Silesia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Morning or afternoon? new study tests best time for heart surgery
Knowledge-focused CompletedThis study aims to understand the impact of time-of-the day on human myocardial tolerance to ischemia-reperfusion by exploring atrial myocardium biopsied during cardiac surgery. Patients scheduled for non-urgent cardiac surgery (coronary artery by-pas graft and/or aortic valve re…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Can better chats improve lung cancer care?
Knowledge-focused OngoingThe purpose of this study is to better understand communication between patients with lung cancer and their clinicians. The investigators are also interested in patient's perceptions of the quality of communication with his/her clinician and how these perceptions may impact patie…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Can a simple valve help tracheostomy patients sleep better and safer?
Symptom relief CompletedLimited research has been done to assess the safety of PMV use during sleep. One prospective study completed by Diez-Gross, et al in 2007 looked at 10 male subjects recorded on two consecutive nights, one night with PMV on and one night with PMV off. All recordings took place in …
Phase: NA • Sponsor: Gaylord Hospital, Inc • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Scientists probe brain and genes to unlock schizophrenia secrets
Knowledge-focused Recruiting nowThis study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three. Patients with mental disorders who have been recruited will take their medication regu…
Sponsor: mingjun Zhong • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Radiotherapy's hidden toll: muscle loss and fatigue under the microscope
Knowledge-focused OngoingThis study examines the extent of systemic muscle loss and the degree of fatigue experienced by breast cancer patients undergoing radiotherapy. This study seeks to identify whether muscle loss occurs outside the radiation fields and if muscle loss is correlated with the degree of…
Sponsor: Essentia Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Virtual skin checks may save patients from unnecessary hospital stays
Knowledge-focused CompletedThe effect of teledermatology on length of hospital admission, length of stay, 30 day readmission rate, and antibiotic use in patients presenting with cellulitis vs pseudocellulitis in an academic emergency department setting.
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Ultrasound at the bedside: a game changer for septic shock?
Knowledge-focused CompletedThis study aims to evaluate the clinical impact of the systematic implementation of point-of-care ultrasound (POCUS) in the management of patients with septic shock in the intensive care unit (ICU). Septic shock is associated with high morbidity and mortality, and its management…
Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Could antibodies be behind POTS? new study investigates
Knowledge-focused Recruiting nowObjective: In this pilot study, we will test the hypothesis that patients with POTS (age 18-60 years) will have a higher percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS.
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Fish oil for moms: could a simple supplement reduce stress and boost baby development?
Knowledge-focused OngoingThe purpose of the study is to test whether nutritional supplementation during pregnancy is associated with 1) improved maternal health during pregnancy; 2) improved infant birth and neurodevelopmental outcomes, and 3) whether the association between nutritional supplementation d…
Phase: NA • Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Fall risk calculator could save lives by predicting who needs urgent care
Knowledge-focused CompletedThis retrospective, multicenter, registry-based cohort study used data from the Pan-Asian Trauma Outcomes Study registry between January 2016 and December 2024. Adult patients with fall-related trauma were included if they had available data on age, sex, emergency department vita…
Sponsor: Mackay Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC