Can extra tdap shots boost Life-Saving plasma?

NCT ID NCT05662852

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study looks at whether giving the Tdap vaccine every 3 months for a year is safe for healthy plasma donors. Normally, this vaccine is given once every 10 years. The goal is to see if more frequent vaccination produces high levels of tetanus antibodies in the plasma, which could be used to make treatments for infections. Participants will receive five vaccinations over 12 months and be monitored for side effects and antibody levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tdap vaccine (tetanus, diphtheria, and acellular pertussis)

What this could lead to

If safe, this could allow more frequent Tdap vaccination in plasma donors, potentially boosting antibody-rich plasma for treating infections.

What could go wrong

This is a small, early-phase study. Giving the vaccine more often than recommended may cause unexpected side effects or weaker immune responses.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diphtheria tetanus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Locations

  • ABO Plasma

    Glassboro, New Jersey, 08028, United States