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116076 trials found · Page 4456 of 5804
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Pause or continue? study tests ACE inhibitor timing to prevent kidney damage
Knowledge-focused CompletedThis clinical trial evaluates whether continuing or withholding ACE inhibitors (specifically Ramipril) before coronary angiography affects the risk of contrast-induced nephropathy (CIN). CIN is a known complication of iodinated contrast exposure, particularly in patients with chr…
Phase: NA • Sponsor: Tanta University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Music eases pain and embarrassment during invasive bladder test, study finds
Symptom relief CompletedUrodynamic testing (UDT) is a diagnostic procedure frequently used to evaluate lower urinary tract dysfunction, including urinary incontinence and voiding difficulties. Despite its diagnostic value, UDT is invasive and often causes discomfort, pain, and embarrassment due to cathe…
Phase: NA • Sponsor: Kocaeli University • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Scientists probe brain networks in depression with High-Tech tools
Knowledge-focused Recruiting nowIn this research study, investigators examine how brain activity changes during tests of emotional processing, attention, and memory using multimodal neuroimaging methods including electroencephalography (EEG), functional magnetic resonance imaging (fMRI), and functional near-inf…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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5000 hepatitis b patients to be tracked for immune clues
Knowledge-focused Recruiting nowThe purpose of this observational study is to follow up on chronic HBV-infected patients over a long period of time to understand the changes in the immune status as age increases and the natural history of chronic HBV infection progresses. The main questions it aims to answer ar…
Sponsor: Nanfang Hospital, Southern Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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VR goggles could ease pain of chest tube insertion
Symptom relief Recruiting nowIntercostal chest drain (ICC) insertion is a common procedure done worldwide to treat and diagnose pleural disease. It is used to evacuate fluid, blood, or air in the cavity from a myriad of causes namely pleural effusions of different etiologies, empyema, hemothorax, chylothorax…
Phase: NA • Sponsor: National University of Malaysia • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Brain scans reveal thinking hurdles in spinal injury patients
Knowledge-focused CompletedIn the case of spinal cord injury, rehabilitation is particularly focused on motor skills. Non-motor impairments such as thinking difficulties did not receive a lot of attention to date. In this research project, the investigators want to find out how thinking difficulties becom…
Sponsor: Swiss Paraplegic Research, Nottwil • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New stitch method may improve knee fracture recovery
Disease control Recruiting nowThis prospective cohort study aims to evaluate the clinical efficacy of high-strength suture modified tension band fixation in treating patellar fractures and compare it with traditional screw-cable tension band fixation. Adult patients (18-55 years) with AO/OTA 34-C1 or 34-C2 pa…
Sponsor: Fuzhou University Affiliated Provincial Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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AI platform aims to help disabled adults manage chronic diseases
Knowledge-focused CompletedThe purpose of this study to pilot test an accessible and inclusive artificial intelligence (AI)-assisted, individualized, family-focused lifestyle modification intervention (AI4CHRON) for health-related quality of life for adults with impaired mobility and chronic medical condit…
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New video program aims to help parents manage Kids' ADHD-Like transition tantrums
Symptom relief CompletedThis study evaluates the feasibility and preliminary impacts of a new parent support program consisting of a series of educational videos, delivered via a popular texting platform. For this pilot project, the program content is focused on teaching parents strategies to better man…
Phase: NA • Sponsor: Okinawa Institute of Science and Technology Graduate University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Oxygen showdown: tight vs. liberal targets in heart failure
Disease control CompletedThis investigator-initiated, prospective, randomized, blinded, multi-center, controlled trial will investigate the effect of a restrictive vs. liberal oxygenation-strategy in patients hospitalized with acute heart failure with pulmonary congestion. Patients will be randomized 1:…
Phase: PHASE2, PHASE3 • Sponsor: Copenhagen University Hospital, Hvidovre • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Mild head injury study aims to sharpen CT scan decisions
Knowledge-focused Recruiting nowThe study aims to assess the incidence of complications, such as intracranial haemorrhages and neurological deficits, in patients with head trauma treated in the emergency departments of the Emilia-Romagna Region and to compare the prognostic accuracy of the Canadian CT Head Rule…
Sponsor: Azienda USL Reggio Emilia - IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Smaller implants may spare patients from extra jaw surgery
Disease control Recruiting nowDental implant treatment, in many cases, may be impeded by anatomical limitations, such as narrow atrophic ridges. In order to overcome that, additional surgical procedures, such as guided bone regeneration, are often required to augment the deficient hard tissue. However, additi…
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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3D-Printed guides may improve jaw surgery precision
Knowledge-focused CompletedThis study will evaluate the accuracy of the use of 3-D printed reduction guide in treatment of mandibular fractures using two different methods of virtual planning.
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Dental implant study tests best temporary teeth for smile health
Symptom relief CompletedThis study aims to evaluate the soft tissue response and prosthetic complications associated with three different types of provisional prostheses used in immediate loading full-arch implant prosthetic treatment. The patients are randomly assigned to the three groups to compare th…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Heart attack patients get a listening ear: new study tests quick emotional support
Symptom relief CompletedBackground: An ST-elevation myocardial infarction (STEMI) is a specific type of heart attack. In a previous study, patients requested more mental and emotional support after a STEMI. To provide this support, the research team worked with hospital staff and patients to create a b…
Phase: NA • Sponsor: Queen's University, Belfast • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Can crowdsourcing help stop the spread? new study tests Community-Driven virus prevention
Prevention Recruiting nowThis study evaluates the impact of an intervention to increase viral transmission behaviors. The intervention will be developed through a crowdsourcing contest.
Sponsor: Wake Forest University Health Sciences • Aim: Prevention
Last updated Jun 27, 2026 14:00 UTC
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Can a smartphone app replace physical therapy visits for shoulder pain?
Symptom relief Recruiting nowThis study will be performed to determine if Band Connect's VirtuaCare™ platform increases patient compliance and provides an effective alternative to current physical therapy treatment while reducing the frequency of visits compared with standard orthopedic physical therapy trea…
Phase: NA • Sponsor: Cedars-Sinai Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Virtual reality glasses ease pain and anxiety during postpartum exam
Symptom relief CompletedThis randomized controlled experimental study aimed to determine the effect of using virtual glasses during uterine tone assessment on anxiety, pain and comfort. The hypotheses of this study were determined as follows: H1-a: Using virtual reality glasses during uterine tone asse…
Phase: NA • Sponsor: Inonu University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Standing ultrasound spots hidden liver tumors better than lying down
Knowledge-focused CompletedObjective: To compare the detection efficacy of standing, supine, and left lateral decubitus ultrasonographic scanning for space-occupying lesions ≤3cm in the liver dome "blind area" and assess the feasibility of standing position as a routine scanning posture, providing a theore…
Sponsor: The First Hospital of Jilin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Gum disease may disrupt Cells' internal cleanup system, study hints
Knowledge-focused CompletedGum disease, including gingivitis and more advanced periodontitis, is a common condition that damages the tissues supporting the teeth. This study looks at how gum disease affects specific proteins inside gum tissue cells that help control how cells communicate between their inte…
Sponsor: Inonu University • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC