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116076 trials found · Page 4452 of 5804
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Can a simple cooling spray ease pain during gynecologic exams?
Symptom relief CompletedThe purpose of this study is to assess if Num vapocoolant spray decreases pain associated with paracervical block in gynecology procedures.
Phase: PHASE4 • Sponsor: Queen's Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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New eye drop aims to erase corneal scars in early trial
Disease control Recruiting nowThis study will enroll subjects with recently formed corneal scars that resulted from a corneal insult presenting and diagnosed within the past approximately 30 days and not less than approximately 7 days. All subjects will be assigned to CSB-001 investigational treatment on Day …
Phase: PHASE1 • Sponsor: Claris Biotherapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Laser or stretching: which eases stubborn neck pain best?
Symptom relief CompletedThis study aimed to investigate and compare the effects of low-intensity laser therapy, a photobiomodulation treatment, and proprioceptive neuromuscular facilitation on pain and disability in individuals with non-specific neck pain. This randomized controlled trial used the Numer…
Phase: NA • Sponsor: Istanbul Gedik University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New imaging technique could simplify brain surgery for Parkinson's
Knowledge-focused CompletedDuring deep brain stimulation procedures in Parkinson's disease (PD), the most important prognostic element is the positioning of the surgical electrode in the subthalamic nucleus which is the anatomical target. The main objective of this project is therefore to compare 2 techniq…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Microplastics found in human Lungs—Could they be linked to cancer?
Knowledge-focused OngoingThis project will study and characterize Microplastic (MP) burden in the lungs of patients undergoing Bronchoalveolar Levage (BAL) in thoracic clinics at Moffitt.
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Can a home exercise program help men on prostate cancer hormone therapy?
Symptom relief CompletedTo refine a remote behavioral exercise training intervention for testing in a larger randomized trial.
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Can family support help black adults lose weight online?
Disease control CompletedThe purpose of this research study is to test the feasibility and acceptability of an interactive counselor -led online family skills training as part of a behavioral weight loss program for Black Adults.
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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BOTOX users report high satisfaction with natural look in new study
Symptom relief CompletedFacial lines that develop from repeated facial expression, such as glabellar lines (GL), lateral canthal lines (LCL), and forehead lines (FHL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin. The purpose of this study is t…
Phase: PHASE4 • Sponsor: AbbVie • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Can a community program boost health in hard-to-reach seniors?
Knowledge-focused Recruiting nowThe goal of this study is to evaluate the impact of the Reach-and-Map project on increasing functional capacity to optimize the functional ability of the vulnerable group of "Hard-to-Reach" older adults through increase the compatibility between their intrinsic capacity and envir…
Phase: NA • Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Can better training for anesthesia teams save lives after surgery?
Knowledge-focused CompletedTools such as surgical plethysmographic index, state entropy, train-of-four monitors exist to optimize the conduct of general anesthesia in intermediate and major risk surgery as defined by the 2022 European Society of Cardiology Guidelines on cardiovascular assessment and manage…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Nerve block may cut painkiller use after back surgery
Symptom relief CompletedThe goal of this interventional study is to is to compare the effect of a tap block versus a placebo in patients undergoing anterior lumbar spine surgery. The main question it aims to answer : • whether tap block can reduce the need for postoperative pain medication Participant…
Phase: NA • Sponsor: Clinique Saint Jean, France • Aim: Symptom relief
Last updated Jul 12, 2026 00:00 UTC
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Laser and peroxide combo shows promise for implant gum disease
Disease control CompletedThe goal of this clinical trial is to learn whether using a special light-activated treatment called photodynamic therapy, or more specifically, its modified version called oxygen high-level laser therapy, using a high-powered diode laser along with 3% hydrogen peroxide, can impr…
Phase: NA • Sponsor: King Abdullah University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New brush and slurry combo could save failing dental implants
Disease control CompletedAim: The aim of this prospective, randomized, parallel arm, blind clinical trial is to compare the clinical and radiographic outcomes following non-surgical treatment of mild peri-implant defects using Labrida Bioclean with or without the application of tetracycline slurry. Res…
Phase: PHASE4 • Sponsor: Aristotle University Of Thessaloniki • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can a diet program help cancer survivors get healthier? new study says maybe.
Knowledge-focused CompletedThis single-arm proof-of-concept pilot will assess the feasibility and acceptability of integrating a survivorship nutrition intervention (BfedBwell) into an existing clinical exercise oncology program (BfitBwell).
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Algae power: new supplement targets gut, anxiety, and immune health
Symptom relief CompletedThis study will be conducted to determine the effect of daily Tetrasol consumption in supporting gut health using assessments of gastrointestinal symptoms (GSRS) and bowel habits (BSS) as primary outcome measures. The investigators also intend to explore fecal and blood biomarker…
Phase: NA • Sponsor: Colorado State University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Can esophageal cancer patients still fight pneumonia after radiation?
Knowledge-focused Recruiting nowTo learn how radiation treatment may affect your responses to vaccines against pneumonia.
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Mindfulness in preschool: a new way to prepare kids for school?
Knowledge-focused CompletedThis study examines the effectiveness of a School-Based Mindfulness Program (SBMP) designed to support attention regulation, emotion regulation, self-awareness, and self-compassion in preschool children aged 48-72 months. The intervention was implemented in preschool classrooms o…
Phase: NA • Sponsor: Hasan Kalyoncu University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Can a virtual geriatric team keep seniors out of the hospital?
Disease control Recruiting nowGet-HEALTH-I study is a retrospective prospective interventional study to evaluate the impact of a geriatric telemanagement program on cost-effectiveness and clinical outcomes in nursing home residents post-hospital discharge.
Phase: NA • Sponsor: Istituto Nazionale di Ricovero e Cura per Anziani • Aim: Disease control
Last updated Jun 26, 2026 14:29 UTC
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No opioids needed: new anesthesia combo may improve breathing during lung surgery
Symptom relief CompletedPatients in the esketamine group was induced with esketamine 0.5 mg/kg, propofol 2 mg/kg, and rocuronium 0.9 mg/kg. Anesthesia is maintained with propofol 5 mg/kg/h and esketamine 0.5 mg/kg/h. Patients in the opioid group was induced with sufentanil 0.5 ug/kg, propofol 2 mg/kg, r…
Phase: NA • Sponsor: Hui Xu • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Can extra help from pharmacists and health workers improve diabetes control?
Disease control Recruiting nowThe purpose of the study is to learn about the best way to enhance pharmacy-related care for diabetes self-management. This research is being done because we want to improve use of medicines and diabetes management among adults with type 2 diabetes and find out which of type of …
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC