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116076 trials found · Page 4415 of 5804
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Ultrasound may replace scopes for Kids' vocal cord checks
Diagnosis Recruiting nowThe goal of this prospective, observational study is to evaluate for the presence of vocal fold motion impairment (VFMI) in the children admitted to the pediatric intensive care unit on noninvasive positive pressure ventilation (NIV PPV). Participants will have two ultrasounds of…
Sponsor: Nemours Children's Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Can thinking and walking at the same time predict falls in cancer survivors?
Knowledge-focused Recruiting nowThe purpose of this research is to examine the impact of peripheral neuropathy on fall risk and quality of life in people who had cancer and neuropathy from cancer treatments. The investigators are interested to find out if the participant have any difficulty with thinking, feeli…
Sponsor: Texas Woman's University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:49 UTC
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Brain zaps to kick the habit? new trial tests rTMS for smoking cessation
Symptom relief Recruiting nowRepetitive transcranial magnetic stimulation (rTMS) is an alternative non-invasive treatment to help people quit smoking. rTMS uses a magnetic field to stimulate regions of the brain that are involved in addiction. The two brain regions that are stimulated are the insula and the …
Phase: PHASE4 • Sponsor: Centre for Addiction and Mental Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Gentle touch: baby massage may boost sleep and bonding
Symptom relief CompletedAs the role of mothers increases in the postpartum period, depression, stress, sleep problems and general needs also increase. Recent studies have emphasized the need to treat more than just the mother's depression in cases of postpartum depression. The increase in the bond with …
Sponsor: University of Yalova • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Tube feeding showdown: which method helps brain injury patients recover faster?
Knowledge-focused CompletedThis was a multicenter randomized controlled study of 98 severe Traumatic Brain Injury patients with tracheostomy. Patients enrolled were divided randomly into the observation group with Intermittent Oro-esophageal Tube Feeding or the control group with Nasogastric tube feeding f…
Phase: NA • Sponsor: Zeng Xi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Mirror trick and zaps help damaged nerves heal better?
Symptom relief CompletedThe goal of this trial is to evaluate the effects of mirror therapy combined with contralaterally controlled functional electrical stimulation on motor recovery and neuroplasticity in patients with peripheral nerve injury. The main questions it aims to answer are Question 1: To c…
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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JARDIANCE under the microscope: Real-World safety check for korean kidney patients
Knowledge-focused CompletedThe primary objective is to monitor the safety profile of JARDIANCE® in Korean patient with chronic kidney disease (CKD) in routine clinical practice. The secondary objective is to monitor the efficacy of JARDIANCE® by evaluating changes in urine albumin-creatinine ratio (UACR) …
Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Talking it out: video chats boost smoking quit intentions in lung cancer patients
Symptom relief CompletedThe effect of online video conferencing on smoking cessation intention in patients diagnosed with lung cancer was investigated.
Phase: NA • Sponsor: University of Gaziantep • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New pain relief for tiny hearts: study tests EXPAREL in kids under 6
Symptom relief Recruiting nowThis Phase 1, multicenter, open-label, randomized, bupivacaine-controlled study is designed to evaluate the pharmacokinetics (PK) and safety of EXPAREL vs. bupivacaine HCl for postsurgical analgesia in pediatric subjects aged 0 to less than 6 years of age undergoing cardiac surge…
Phase: PHASE1 • Sponsor: Pacira Pharmaceuticals, Inc • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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New study aims to map how stargardt disease worsens over time
Knowledge-focused Recruiting nowThis is an Observational Study to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene This is a multicenter study which will enroll approximately 75 subjects
Sponsor: Splice Bio • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:54 UTC
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Real-World study reveals how breast cancer drugs are actually used in portugal
Knowledge-focused CompletedAssess and characterize the real-world cyclin-dependent kinase 4/6 inhibitor (CDKI) use in advanced/metastatic breast cancer (a/mBC), evaluate treatment persistence, and quantify CDKI dose adjustments in Portugal. This study used secondary data from the IQVIA database that colle…
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Writing your future self: a 20-Minute exercise may curb risky drinking after high school
Knowledge-focused OngoingThe purpose of the proposed research is to evaluate (1) whether a future possible self task (FPST) can lead to changes drinking identity (DI; how much one associates one's self with drinking) and (2) whether the FPST and changes in drinking identity also change indicators of alco…
Phase: NA • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Scientists launch largest Real-World study of rare angiosarcoma
Knowledge-focused Recruiting nowThis study will be a multi-institutional, prospective, observational study of patients with localized primary AS of any site within ISG and RTR centers. Patients will be treated according to clinical practice of the center and according to ISG clinical recommendations on localize…
Sponsor: Italian Sarcoma Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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AI reads prostate scans to predict survival
Knowledge-focused Recruiting nowThe primary aim of the present study is to evaluate how automatically calculated (by an AI-based method) tumour burden, measured as tumour volume (TV) and as tumour uptake (TU: TV x SUVmean) in the prostate/prostate bed, pelvic lymph nodes, distant lymph nodes, bone and as the to…
Sponsor: Elin Tragardh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New shot aims to prevent clots without bleeding risk
Disease control CompletedThis was a Phase 1, randomized, double-blind, placebo-controlled, single ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of subcutaneously administered SRSD107 in Chinese healthy subjects. SRSD107 is a synthetic, chemica…
Phase: PHASE1 • Sponsor: Sirius Therapeutics Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New wrinkle treatment shows promise in asian trial
Symptom relief CompletedFacial lines that develop from repeated facial expression, such as glabellar lines (GL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin. The purpose of this study is to evaluate the safety and efficacy of AGN-151586 compar…
Phase: PHASE3 • Sponsor: AbbVie • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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Fiber-Rich diet may tame blood sugar and hunger in overweight adults
Symptom relief CompletedThis study will systematically investigate the effects of a diet with decreased energy density, reduced glycaemic index, and significantly increased dietary fibre, on post-prandial glycaemic response, satiety, gastrointestinal tolerability and gut microbiota composition and funct…
Phase: NA • Sponsor: University College Cork • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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New app aims to ease tough transition for young liver transplant patients
Knowledge-focused Recruiting nowThe study is part of the MACROLIVER Project, whose main objective is to create a digital tool for patients and caregivers for the management of liver disease that allows the optimization of therapy and/or the treatment process, even remotely. Such a tool not only reduces the move…
Sponsor: FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New nerve block may beat morphine for scoliosis surgery pain
Symptom relief CompletedThe aim of this study is to compare the analgesic efficacy of mid-transverse process to pleura (MTP) block and intrathecal morphine in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New blood test benchmarks for pregnant women could prevent dangerous clots
Knowledge-focused CompletedPregnancy is associated with significant changes in several aspects of haemostasis, especially an imbalance between procoagulant and anticoagulant factors. These changes contribute to creating a state of hypercoagulability, mainly at the end of pregnancy and during the post-partu…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC