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127005 trials found · Page 4413 of 6351
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Blood sugar dips at night linked to muscle wasting in liver disease patients
Knowledge-focused Recruiting nowFasting blood glucose is maintained by hepatic production of glucose from glycogenolysis or gluconeogenesis. In cirrhosis, glycogen storage capacity is reduced, with a consequent increase in gluconeogenesis to maintain blood glucose levels. Hypoglycaemia is particularly common du…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:39 UTC
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Can a flexitarian diet ease gut pain in eating disorder recovery?
Knowledge-focused Recruiting nowThis prospective observational study investigates the development of gastrointestinal (GI) symptoms in patients with anorexia nervosa (AN) and bulimia nervosa (BN) during multi-week inpatient weight rehabilitation. The study explores how the predominant nutritional strategy-flexi…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Could a bedtime drink be the key to better sleep?
Symptom relief Recruiting nowThis study aims to examine the effectiveness of Avance eZZe drink with liposomal technology in improving sleep quality. Participants will be randomly assigned to either the placebo group, Avance eZZe drink group, and Avance eZZe drink without liposomal group, with 25 participants…
Sponsor: TCI Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Cancer-Fighting T-Cell therapy trial for GI cancers withdrawn before start
Disease control CancelledBackground: Gastrointestinal (GI) cancer affects the organs (such as the stomach, large and small intestine, pancreas, colon, liver, and biliary system) of the digestive tract. In some participants who have had surgery for GI cancer, blood tests show that the cancer has spread d…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 26, 2026 15:48 UTC
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Spiritual support may ease anxiety in advanced cancer patients
Symptom relief OngoingThe purpose of this study is to address the need for effective spiritual care support for patients with lung and gastrointestinal cancer. This study will examine how spiritual care affects spiritual wellbeing, anxiety, depression, satisfaction with spiritual care, and quality of …
Sponsor: Indiana University • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Could a simple walk before surgery save you from complications?
Knowledge-focused Recruiting nowPatients with abdominal wall incisional hernia often have numerous comorbidities, making management complex. To date, no study has described the relationship between preoperative physical activity and the occurrence of complications, particularly severe ones, after incisional he…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Fatigue fix? study tests energy supplements against placebo
Symptom relief CompletedA randomized, double-blind, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on fatigue and related health outcomes
Sponsor: Radicle Science • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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New nerve block could cut morphine use after gallbladder surgery
Symptom relief Recruiting nowPostoperative pain after laparoscopic cholecystectomy can be considerable. Regional techniques such as erector spinae plane (ESP) block or transversus abdominis plane (TAP) block may be suitable for patients at increased risk of postoperative pain. The deep rectus sheath block is…
Sponsor: Istinye University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Which exercise eases back pain best? new study recruits students
Symptom relief Recruiting nowLow Back Pain (LBP) as estimates show that up to 84% of adults will experience LBP at some point in their lifetime, ranking it as a leading cause of disability globally. If the pain lasts more than 12 weeks and remains difficult to manage effectively, it can be called Chronic low…
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 26, 2026 16:59 UTC
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300,000 people to test if digital workouts improve health
Knowledge-focused By invitation onlyThe purpose of this study is to create a research repository, composed of data collected during a digital physical activity program delivered by Sword Move to individuals undergoing those programs. Sword Move intends to increase physical activity levels to stimulate the adoption …
Sponsor: Sword Health, SA • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:33 UTC
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Could this toothpaste beat gum disease?
Disease control CompletedThe aim of this study is to evaluate the ability of an experimental toothpaste, containing 0.454 percent (%) Stannous Fluoride (SnF2) to improve gingival health and reduce plaque accumulation compared to a regular fluoride toothpaste (reference dentifrice) in participants with lo…
Sponsor: HALEON • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Booklets beat anxiety? new study tests simple tool for breast cancer patients
Symptom relief Stopped earlySince late 2019, the French association "MON PARCOURS DE VIE" has developed books donated by caregivers at cancer centers in France. These documents are available online: https://www.monparcoursdevie.fr/. They are highly acclaimed by women suffering from the breast cancer, as wel…
Sponsor: Institut de Cancérologie de Lorraine • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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Legal aid may ease burden for cancer caregivers
Symptom relief Recruiting nowThis is a single center single-arm, pilot study of proactive and early connection with free legal care services for patient-caregiver dyads affected by colorectal cancer to assess the feasibility, acceptability, and preliminary efficacy of this intervention in improving financial…
Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Symptom relief
Last updated Jun 26, 2026 17:38 UTC
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Hidden sleep disorder may worsen schizophrenia, new study investigates
Knowledge-focused Recruiting nowThis research project aims to evaluate the prevalence of comorbid OSA and its impact on disease progression among hospitalized schizophrenia patients using non-wearable devices.
Sponsor: Taipei Medical University Shuang Ho Hospital • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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New study aims to decode pain in kidney disease patients
Knowledge-focused Recruiting nowOver 60% of patients with ADPKD suffer from pain, mostly in the abdomen, flank and back, often leading to the diagnosis. It is challenging to manage and cure the pain; approximately 39% of patients are not satisfied with their pain treatment, since the pain prevents them from doi…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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AI vs. radiologist: who spots prostate cancer better?
Knowledge-focused Recruiting nowThis study will enroll participants who are undergoing an MRI before a prostate biopsy due to suspected prostate cancer. The purpose of this study is to see if the use of Artificial Intelligence (AI) helps detect lesions on an MRI better than a radiologist not using AI. The AI Ra…
Sponsor: Case Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Robot-Assisted mastectomy: smaller scars, same safety?
Disease control Recruiting nowThis study aims to learn whether a handheld robotic device, called the HandX, can help surgeons safely perform a minimally invasive nipple-sparing mastectomy. This type of mastectomy uses a small incision at the side of the breast to remove breast tissue while keeping the skin an…
Sponsor: Vasileios Kalles • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New study tests natural supplement for fatigue relief
Symptom relief Recruiting nowThis study explores how Heart \& Soil's Lifeblood impacts iron levels and energy.
Sponsor: Efforia, Inc • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Scientists hunt for genes behind hernias in baby boys
Knowledge-focused OngoingThe aim of the project is to elucidate the genetic etiology underlying the development of the processus vaginalis (PV) in male children with indirect inguinal hernia (IIH) and undescended testis (UT), through the investigation of potential variants in the INSL3, WT1, and GATA6 ge…
Sponsor: Trakya University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New study aims to unlock secrets of rare inflammatory diseases
Knowledge-focused Recruiting nowAutoinflammatory diseases are part of a heterogeneous group of diseases that manifest themselves through an inflammatory reaction in their initial phase (innate immunity) that is activated inappropriately: either because the reaction is too strong or because it is unjustified (fo…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC