New nerve block could cut morphine use after gallbladder surgery

NCT ID NCT06976320

Recruiting now Symptom relief Sponsor: Istinye University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new type of nerve block, called a deep rectus sheath block, to see if it can reduce pain and the need for morphine after laparoscopic gallbladder removal. The trial will involve 60 adults aged 18 to 80 who are scheduled for this surgery. Researchers will measure how much morphine patients need in the first 24 hours after surgery and their pain scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep rectus sheath block (a nerve block injection)
What this could lead to: If it works, this could offer a better way to manage pain after gallbladder surgery, reducing the need for strong painkillers like morphine.
What could go wrong: This is a small, early-stage study with only 60 people, so results may not apply to everyone. The block is new and has only been tested in a few case reports, so its effectiveness and safety are not yet proven.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA CHOLECYSTECTOMY, LAPAROSCOPIC POSTOPERATIVE PAIN

Contacts and locations

Locations

Istinye University Hospital
RECRUITING

Istanbul, Turkey (Türkiye)

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