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127426 trials found · Page 4245 of 6372
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Microchip implanted in liver tumors could personalize cancer treatment
Knowledge-focused Recruiting nowMicrodevices have been used to ascertain in vivo drug response, which can lead to improved cancer treatment delivery; however, they have not been evaluated for liver tumors. This is a prospective, phase 1 safety study of percutaneous placement and surgical retrieval of a microdev…
Early phase 1 • Sponsor: Northwell Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Can sound waves reboot the brain after stroke?
Knowledge-focused Recruiting nowThe goal of this research study is to optimize the parameter of Low-Intensity Focused Ultrasound Stimulation (LIFUS) that is most effective in changing cortical excitability and motor learning skills in patients who suffered a stroke. The researchers hope to answer two questions.…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Robotic legs go Head-to-Head: which exoskeleton helps paralyzed people walk better?
Knowledge-focused CompletedThe purpose of this study is to compare two types of wearable lower-extremity exoskeletons -a self-balancing device lower-extremity exoskeleton and a user-balancing device lower-extremity exoskeleton-to better understand their effects on the physiological responses to walking and…
Sponsor: Georgia Institute of Technology • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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New study checks safety of RSV prevention drug in vulnerable infants
Prevention OngoingThis is a Phase IV, prospective, open-label, multicentre study to evaluate the safety of palivizumab IM injection for the prevention of severe LRTD in Indian infants and children who are at high-risk of RSV disease. All enrolled participants will receive palivizumab 15 mg/kg IM i…
Sponsor: AstraZeneca • Aim: Prevention
Last updated Sep 10, 2026 15:00 UTC
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Tiny lung puffs during surgery could speed recovery
Knowledge-focused By invitation onlyThis study aims to determine the optimal interval for periodic alveolar recruitment maneuvers (PARM) that can achieve effective lung re-expansion in 90% of patients undergoing intraoperative mechanical ventilation during abdominal laparoscopic surgery in the low Trendelenburg pos…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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New pain block may beat epidural for cancer surgery recovery
Symptom relief Recruiting nowThis study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal cancer surgery.
Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Could your gut bacteria be linked to anxiety? new study investigates
Knowledge-focused CompletedThis study aims to investigate the etiology of anxiety, depression, and panic disorders, providing new evidence and insights into the root causes and effective treatments, potentially offering a novel approach to achieving complete recovery.
Sponsor: University of Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Pause your Weight-Loss shot before a scope? new study investigates
Knowledge-focused Not yet recruitingA retrospective observational study to explore the impact of discontinuing GLP-1 receptor agonists for two weeks prior to upper endoscopy on the risk of gastric retention
Sponsor: Fudan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New program aims to help older dialysis patients manage falls, memory, and daily tasks
Knowledge-focused By invitation onlyThe objectives of this study are to refine the dialysis care model with key stakeholder input and conduct a pilot randomized controlled trial (RCT) to obtain evidence critical to inform a definitive RCT.
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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Chewing gum may soothe chemo nausea: new study tests ginger and cinnamon
Symptom relief Not yet recruitingThis randomized controlled clinical trial aims to evaluate the effectiveness of chewing gum with different natural flavors in reducing postoperative nausea and vomiting (PONV) following Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC). Adult patients undergoing PIPAC will…
Sponsor: Fenerbahce University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Light boost for Kids' cavity treatment?
Disease control CompletedThis observational clinical study investigates the effect of silver diamine fluoride (SDF) and its activation with light-emitting diode (LED) on residual caries activity after caries excavation in Class II primary molar cavities. Dental caries in children remains highly prevalent…
Sponsor: Çanakkale Onsekiz Mart University • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Quick fluid bolus or slow drip? study tests best way to calm Baby's heartbeat in labor
Symptom relief CompletedThis randomized trial compared a normal saline bolus regimen with continuous normal saline infusion. The participants were low-risk pregnant women at term with Category II fetal heart rate tracings. Both groups were prescribed 1,000 mL of normal saline through the same volumetric…
Sponsor: Queen Savang Vadhana Memorial Hospital, Thailand • Aim: Symptom relief
Last updated Aug 19, 2026 00:00 UTC
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New study aims to sharpen PET/CT accuracy for cancer patients
Knowledge-focused Not yet recruiting-To measure SUVs by using different correction methods in oncological PET/CT imaging.
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Wearable patch could keep tabs on spine surgery patients without wires
Knowledge-focused Recruiting nowThe goal of this feasibility study is to explore the use of wireless continuous vital sign monitoring in an orthopaedic setting among orthopaedic nurses and patients undergoing adult spinal deformity surgery. In addition to the standard care National Early Warning Score the parti…
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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New nerve block may cut opioid use after gallbladder surgery
Symptom relief Recruiting nowThis study aims to compare the analgesic effect of retro superior costotransverse ligament space block vs erector spinae plane block to Achieve high-quality perioperative opioid-sparing effect and postoperative analgesia after laparoscopic cholecystectomy with optimum hemodynamic…
Sponsor: Zagazig University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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AI coach for colonoscopies: less blurry views, better exams?
Knowledge-focused Not yet recruitingThis study will employ a prospective, multicenter, controlled design. It will be conducted across multiple centers, with participated centers randomly assigned to one of four groups: Group A, Group B, Group C, and Group D. The research will primarily focus on the AI-based analys…
Sponsor: The First Affiliated Hospital of Anhui Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Army tests 'Level Up' training to curb suicide and risky behavior in new recruits
Knowledge-focused Recruiting nowThis project will evaluate the effectiveness of Level Up: Boost Your Life Skills ("Level Up"), a strengths based, military-specific life skills training program. The goal is to determine whether Level Up can decrease suicidal-related behaviors (SRBs) and other harmful behaviors, …
Sponsor: Uniformed Services University of the Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New study tests video to stop people from ignoring cancer info
Knowledge-focused OngoingHealth information avoidance is an overlooked threat to the reach and effectiveness of health communication. To fully realize the benefits of our sizeable investments in health messaging, it is necessary to identify strategies for reducing health information avoidance. The resear…
Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Tiny greens, big dreams: microgreens may boost athlete sleep
Symptom relief CompletedThis study aims to investigate the effects of Microgreen use on sleep architecture in athletes. Sleep architecture refers to the structural organization of sleep, including the distribution of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep stages, sleep onset la…
Sponsor: Çanakkale Onsekiz Mart University • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Pee power: urine test could unlock chlamydia immunity secrets
Knowledge-focused Recruiting nowThe goal of this observational study is to learn if we can identify immune biomarkers in first-void urine and vaginal brush samples in Chlamydia trachomatis (CT) positive adult women. Participants will self-collect a first-void urine sample, self-collect a vaginal brush, and a bl…
Sponsor: Universiteit Antwerpen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC