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127005 trials found · Page 3594 of 6351
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Better ankle implant aims to last longer and reduce pain
Disease control OngoingAn ankle replacement procedure consists of replacing the worn-out joint surfaces of the ankle with metal and plastic components that are shaped to allow continued movement of the ankle. There are several different types of ankle replacement available. Infinity ankle implants are …
Sponsor: Northumbria Healthcare NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Morning or evening? timing your RA pill could boost relief
Disease control Recruiting nowThe aim of this study is to offer patients two treatment options: morning or evening administration of a JAK inhibitor prescribed within the framework of its marketing authorization, according to the EULAR response. The objective is to determine whether evening administration in…
Sponsor: Centre Hospitalier Princesse Grace • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New program aims to help kids eat better after leaving the hospital
Disease control Recruiting nowThe goal of this stepped wedge cluster randomized trial is to compare nutritional care after discharge to an intervention in children term born - 18 years old discharged with newly initiated nutritional care. The main question it aims to answer is: To investigate whether a tail…
Sponsor: Erasmus Medical Center • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Phone app helps new moms breastfeed longer
Symptom relief OngoingDuring Chinese mothers' doing the month, they are often housebound and find it difficult to attend group support or seek help during the first month postpartum which is the critical period in sustaining exclusive breastfeeding and at high risk of weaning. This can adversely affec…
Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Pain is not equal: study probes how race and income alter back pain
Knowledge-focused Recruiting nowThe purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP).
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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New study tracks pregnancy in women with neuroimmune diseases
Knowledge-focused Recruiting nowNeuroimmune diseases are more prevalent among women of reproductive age. Studies have shown that neuroimmune diseases may impact fertility. Therefore, effective management of neuroimmune diseases during pregnancy is particularly important. This study included a follow-up period o…
Sponsor: Third Affiliated Hospital, Sun Yat-Sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Could a virtual support group ease anxiety after 'Broken Heart' syndrome?
Symptom relief Recruiting nowThe study hypothesis is that participants enrolled in a virtual Takotsubo support group will have significantly less anxiety at one year.
Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New study scans brains of kids with autism to uncover social thinking secrets
Knowledge-focused Recruiting nowThe main goal of this study is to investigate anatomo-functional brain abnormalities associated with autism spectrum disorders using a multimodal brain imaging approach, as well as its links to social cognition difficulties measured using eye-tracking
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New study aims to keep dutch workers mentally healthy with custom stress prevention
Prevention By invitation onlyThe objective of the current study, Vital@Work, is to keep employees in the Netherlands vital on the long term by preventing work-related mental health problems. Therefore, we test an evidence based Participatory Approach (PA) to compose a mental health program tailored to behavi…
Sponsor: Amsterdam UMC, location VUmc • Aim: Prevention
Last updated Jun 26, 2026 18:50 UTC
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New IVF method passes first long-term child development check
Knowledge-focused CompletedThe investigators conduct a long-term follow-up at five years on offspring born from our randomized controlled trial (RCT) to investigate whether or not there is any difference in developmental outcomes in children born after capacitation IVM (CAPA IVM) compared with conventional…
Sponsor: Mỹ Đức Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:01 UTC
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Gene-edited stem cells: a lasting fix for sickle cell?
Disease control OngoingCADPT03A12001 is a prospective, multi-center study that is designed to follow all enrolled patients who have received treatment with OTQ923 for long-term safety and efficacy.
Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Blood bandage beats salt water for kids' spoke injuries?
Disease control CompletedThis study is testing whether autologous platelet rich plasma (PRP) dressings are more effective than normal saline dressings in treating heel pad injuries caused by motorcycle wheel spokes among children in Pakistan. PRP is prepared from a child's own blood and contains natural …
Sponsor: Services Institute of Medical Sciences, Pakistan • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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New scan could spot hidden cancers
Diagnosis CompletedThe study should evaluate the biological distribution of \[123I\]I-DARPIN-Ec1 in patients with lung and ovarian cancer The primary objective are: 1. To assess the distribution of \[123I\]I-DARPIN-Ec1 in normal tissues and tumors at different time intervals. 2. To evaluate dosim…
Phase 1 • Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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AI model aims to predict ICU deaths from superbug blood infections
Knowledge-focused CompletedUsing our own patient data, our study aimed to predict mortality that can develop in Carbapenem-resistant Gram-negative bacilli bloodstream infections with a machine learning-based model. In the intensive care unit, patients with bloodstream infections, both with and without mor…
Sponsor: Kocaeli University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New study aims to stop stomach cancer before it starts
Knowledge-focused Recruiting nowThe purpose of this study is to create a registry of participants with precursor lesions for gastric cancer, including gastric atrophy, intestinal metaplasia, and dysplasia. Normal controls and individuals with gastric cancer for comparison of baseline characteristics will also b…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Online wellness program aims to boost resilience after brain injury
Symptom relief Recruiting nowThis randomized trial aims to determine the effectiveness a virtual wellness intervention program in individuals with traumatic brain injury (TBI). Participants will be randomized at enrollment into two groups: immediate treatment (IT) and delayed treatment (DT) group. This study…
Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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A simple head turn could make airway tube placement easier and safer
Knowledge-focused CompletedThis study evaluated how simple external airway maneuvers affect the alignment of the left main bronchus during placement of a left-sided double-lumen endotracheal tube. Adults undergoing elective thoracic surgery requiring one-lung ventilation were enrolled. During double-lumen…
Sponsor: Taipei Veterans General Hospital, Taiwan • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC
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New combo therapy tested for tough pancreatic cancer
Disease control CompletedThis study aims to determine the safety and tolerability of combining sequential therapy of Irreversible Electroporation (IRE) and Immunotherapy (IO) for patients with locally advanced unresectable pancreas cancer following first-line treatment with chemotherapy and ablative ster…
Phase 1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Laser acupuncture may soothe itching in kidney patients
Symptom relief CompletedSixty patients were randomly assigned to either the experimental group (n=30) receiving laser acupuncture or the control group (n=30) receiving sham laser acupuncture. Treatment sessions were conducted during dialysis sessions. The experimental group received laser acupuncture at…
Sponsor: Dalin Tzu Chi General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Could a simple skincare routine soothe psoriasis Flare-Ups?
Symptom relief CompletedSubjects having mild-to-severe plaque psoriasis, with active target lesion plaques, and currently on or starting a prescription treatment for plaque psoriasis will apply a topical skincare regimen to one side of the body. Evaluations of the regimen's efficacy will be conducted at…
Phase 4 • Sponsor: Galderma R&D • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC