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127005 trials found · Page 3564 of 6351
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New hope for back pain? study tests sugar injections against standard rehab
Symptom relief CompletedChronic low back pain (CLBP) represents one of the leading causes of long-term disability among adults and places a substantial strain on healthcare systems globally. The clinical course of CLBP is highly heterogeneous, with considerable variability in symptom persistence and fun…
Sponsor: Balnear and Rehabilitation Sanatorium Techirghiol • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Which filling wins for Kids' cavities? a Head-to-Head test
Disease control CompletedTo evaluate the clinical and radiographic performance of Alkasite restorative material versus glass ionomer in restoration of primary molars.
Sponsor: Cairo University • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Smart board could bring arm rehab home for brain injury patients
Symptom relief Recruiting nowThe aim is to clinically validate the clinical efficacy, usability, and safety of home-based upper limb rehabilitation training using the Neofect Smart Board by comparing the effects between a group using the home-based Neofect Smart Board and a group performing conventional home…
Sponsor: Samsung Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Blood clues: could type 1 diabetes change how children's blood works?
Knowledge-focused Recruiting nowDiabetes mellitus is a group of chronic metabolic diseases characterized by hyperglycemia .Type 1 diabetes is a heterogeneous disease related to the destruction of pancreatic beta cells and is a result of absolute lack of insulin * Diabetes mellitus has been traditionally looked…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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High-Energy showdown: 360J vs 200J shocks for AFib
Symptom relief Recruiting nowCan Electrical Cardioversion (ECV) for AF be improved. It is the preferred method to restore sinus rhythm in patients with AF in whom a rhythm-control strategy is pursued. Hypothesis: ECV success rates will be greater with a biphasic defibrillator with maximum energy of 360J (®…
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Zapping a heel nerve: new hope for chronic foot pain?
Symptom relief CompletedThis prospective single-arm pilot interventional study aims to evaluate the effectiveness of ultrasound-guided radiofrequency ablation of the inferior calcaneal nerve in patients with chronic heel pain refractory to conservative treatments. Patients with plantar fasciitis or calc…
Sponsor: Şahide Eda Artuç • Aim: Symptom relief
Last updated Sep 10, 2026 06:00 UTC
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Could a simple ultrasound replace an invasive scope for Post-Surgery uterine checks?
Knowledge-focused CompletedThis study will focus on evaluation of the uterine cavity after operative hysteroscopy using three dimensional transvaginal ultrasonography and office hysteroscopy to detect and residual or recurrent abnormalities or intrauterine adhesions to optimize the results of operative hys…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Platelet injections may ease jaw arthritis pain
Symptom relief CompletedStudying effectiveness of prp with prf comparing with prp or prf for mangement of tmj osteoarthritis as result in pain and mandibular movement in adult pt
Sponsor: Aliaa Babekir Ahmed Mohamed • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Can two bronchitis drugs be taken together safely?
Knowledge-focused CompletedThis Phase 1 study will evaluate the safety and drug-drug interactions of AG2203L and AG2203E in healthy adult participants. Participants will receive AG2203L and AG2203E alone and in combination during three treatment periods according to one of six randomly assigned treatment s…
Phase 1 • Sponsor: Ahn-Gook Pharmaceuticals Co.,Ltd • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Pilates plus Hands-On therapy shows promise for back pain relief
Symptom relief CompletedThe purpose of this study is to compare the effects of manual therapy alone and manual therapy combined with Reformer Pilates exercises in women with chronic low back pain (CLBP).
Sponsor: Uskudar University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Scientists hunt for hidden COVID remnants in long COVID patients
Knowledge-focused Recruiting nowBackground: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 have symptoms that last long after the active infection ends. This is called "long COVID." Sometimes, long COVID can affect the nerves and cause problems with sleep, thinking, the sen…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Nerve block during chest surgery may cut recovery risks
Knowledge-focused Recruiting nowThis study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Blood test may reveal hidden organ damage in sepsis patients
Knowledge-focused OngoingThis is a prospective, non-randomized study investigating if organ damage and immune changes can be measured by liquid biopsy NGS through advanced analytical methods.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Breathing workouts may ease Obesity-Linked lung problems
Symptom relief Recruiting nowThe aim of the project will be to assess the functional condition of the respiratory tract and inflammation resulting from obesity, as well as the possibility of using inspiratory muscle training as a factor reducing the occurrence of dysfunction in the respiratory system.
Sponsor: Wroclaw University of Health and Sport Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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AI could spot COPD trouble early from home ventilator data
Knowledge-focused Recruiting nowThis study will look at people with COPD who use a home breathing machine called non-invasive ventilation (NIV). NIV machines collect information about your breathing, such as air flow, pressure, and mask leaks. Researchers want to use a computer program, called artificial intel…
Sponsor: Corporacion Parc Tauli • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Pill before surgery eases fear and pain for cataract patients
Symptom relief Recruiting nowPhacoemulsification is one of the most used surgical methods for cataract surgery today, and the surgeries are under the anesthetic and sedative to make it comfortable and safe for patients. The most important issue is which method is the best for reducing the patient's anxiety, …
Phase 4 • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Whole foods diet for teens: a new hope against obesity?
Disease control Recruiting nowThis study will address the following aims: Aim 1: Conduct an 8-week pilot RCT to examine the effects of a whole foods diet intervention on body adiposity in adolescents with obesity. Aim 1a (Primary): Evaluate intervention effectiveness on total fat mass following the 8-week i…
Sponsor: Vanderbilt University • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New study tests smarter ways to start opioid treatment in the ER
Knowledge-focused CompletedThis study is stage 1 of a larger study which refines and optimizes the EMBED\* clinical decision support (CDS; see NCT03658642) to increase number of ED physicians following standard of care for the administration of buprenorphine to appropriate patients with opioid use disorder…
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Inside the ICU: what makes teams click or crack?
Knowledge-focused Recruiting nowThe goal of this ethnographic study is to observe how healthcare professionals work together in an intensive care unit (ICU). The main questions it aims to answer are * How do healthcare staff work together in everyday ICU settings? * What helps people work together in ICUs? * W…
Sponsor: King's College London • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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Can exercise and education improve breathing for Oxygen-Dependent patients?
Symptom relief Recruiting nowEvaluation of the effect of pulmonary rehabilitation on patients with high flow oxygen therapy
Sponsor: Chinese PLA General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC